umuD:Quickview: Difference between revisions

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===Notes===
===Notes===
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LexA regulon. Autocleavage removes the first 24 amino acids to form UmuD', required for mutageneic translesion synthesis (TLS). UmuD and UmuD' are intrinsiclly disordered proteins (IDPs) that can nonetheless form stable dimers (Simon, 2008).<ref name='LIB:EcoGene'/>





Revision as of 00:47, 3 March 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

umuD (synonyms: ECK1171, b1183, JW1172, uvm)[1]

Product(s)

UmuD product[1]: DNA polymerase V, subunit D product, B1183 product

Description

SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC[2][3]

Component of DNA polymerase V[3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): umuDC[2], OP00250

Regulation/Activity


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See Help:Quickview for help with entering information in the Quickview table.

Notes

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LexA regulon. Autocleavage removes the first 24 amino acids to form UmuD', required for mutageneic translesion synthesis (TLS). UmuD and UmuD' are intrinsiclly disordered proteins (IDPs) that can nonetheless form stable dimers (Simon, 2008).[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.