cbl:Gene Product(s): Difference between revisions

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[[Category:GO:0003700_!_transcription_factor_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003700_!_transcription_factor_activity GO:0003700]
GO:0003700
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transcription factor activity
transcription factor activity
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]
GO_REF:0000002
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR000847 InterPro:IPR000847]
InterPro:IPR000847
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F
F
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[[Category:GO:0003677_!_DNA_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003677_!_DNA_binding GO:0003677]
GO:0003677
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DNA binding
DNA binding
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
GO_REF:0000004
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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[http://www.uniprot.org/keywords/KW-0238 SP_KW:KW-0238]
SP_KW:KW-0238
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F
F
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[[Category:GO:0006350_!_transcription]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006350_!_transcription GO:0006350]
GO:0006350
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transcription
transcription
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
GO_REF:0000004
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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[http://www.uniprot.org/keywords/KW-0804 SP_KW:KW-0804]
SP_KW:KW-0804
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P
P
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[[Category:GO:0006355_!_regulation_of_transcription,_DNA-dependent]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006355_!_regulation_of_transcription,_DNA-dependent GO:0006355]
GO:0006355
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regulation of transcription, DNA-dependent
regulation of transcription, DNA-dependent
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
GO_REF:0000002<br />GO_REF:0000004
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR000847 InterPro:IPR000847]<br />[http://www.uniprot.org/keywords/KW-0805 SP_KW:KW-0805]
InterPro:IPR000847<br />SP_KW:KW-0805
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P
P
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NOT
NOT
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[[Category:GO:0006790_!_sulfur_metabolic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006790_!_sulfur_metabolic_process GO:0006790]
GO:0006790  
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sulfur metabolic process
sulfur metabolic process
|[[PMID:10506196]]<ref name=PMID:10506196/>
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PMID:10506196
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IDA: Inferred from Direct Assay
IDA: Inferred from Direct Assay
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[[Category:GO:0006350_!_transcription]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006350_!_transcription GO:0006350]
GO:0006350  
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transcription
transcription
|[[PMID:10506196]]<ref name=PMID:10506196/>
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PMID:10506196  
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IDA: Inferred from Direct Assay
IDA: Inferred from Direct Assay
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NOT
NOT
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[[Category:GO:0019344_!_cysteine_biosynthetic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0019344_!_cysteine_biosynthetic_process GO:0019344]
GO:0019344  
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cysteine biosynthetic process
cysteine biosynthetic process
|[[PMID:10506196]]<ref name=PMID:10506196/>
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PMID:10506196
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[[Category:GO:0016564_!_transcription_repressor_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016564_!_transcription_repressor_activity GO:0016564]
GO:0016564  
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transcription repressor activity  
transcription repressor activity  
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[[Category:GO:0005737_!_cytoplasm]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0005737_!_cytoplasm GO:0005737]
GO:0005737  
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cytoplasm  
cytoplasm  
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[[Category:GO:0016563_!_transcription_activator_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016563_!_transcription_activator_activity GO:0016563]
GO:0016563  
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transcription activator activity
transcription activator activity
|[[PMID:10506196]]<ref name=PMID:10506196/>
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PMID:10506196  
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IDA: Inferred from Direct Assay
IDA: Inferred from Direct Assay
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[[Category:GO:0045883_!_positive_regulation_of_sulfur_utilization]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0045883_!_positive_regulation_of_sulfur_utilization GO:0045883]
GO:0045883
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positive regulation of sulfur utilization
positive regulation of sulfur utilization
|[[PMID:10506196]]<ref name=PMID:10506196/>
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PMID:10506196  


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<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span>
<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span>
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<span id="Structure"></span><big>'''Structure'''</big>
<span id="Structure"></span><big>'''Structure'''</big>
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==References==
==References==
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<references/>
<references/>
__NOTOC__
__NOTOC__

Revision as of 21:39, 16 February 2009

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Cbl

Synonyms

DNA-binding transcriptional activator of cysteine biosynthesis[1], B1987[2][1], Cbl[2][1]

Product description

Cbl transcriptional activator[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0003700

transcription factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000847

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0003677

DNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0006350

transcription

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR000847
SP_KW:KW-0805

P

Seeded from EcoCyc 12.5 [4]

complete

NOT

GO:0006790

sulfur metabolic process

PMID:10506196[5]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc 11.1[3].

This is not part of the sulfur metabolic process. See below for the regulation of sulfur utilization.

complete

GO:0006350

transcription

PMID:10506196[5]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc 11.1[3].

complete

NOT

GO:0019344

cysteine biosynthetic process

PMID:10506196[5]

P

Seeded from EcoCyc 11.1[3].

required field missing

GO:0016564

transcription repressor activity

F

Seeded from EcoCyc 10.6[2].

required fields missing

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0016563

transcription activator activity

PMID:10506196[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 11.1[3].

complete

GO:0045883

positive regulation of sulfur utilization

PMID:10506196[5]

IDA: Inferred from Direct Assay

P

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MNFQQLKIIR EAARQDYNLT EVANMLFTSQ SGVSRHIREL EDELGIEIFV RRGKRLLGMT
EPGKALLVIA ERILNEASNV RRLADLFTND TSGVLTIATT HTQARYSLPE VIKAFRELFP
EVRLELIQGT PQEIATLLQN GEADIGIASE RLSNDPQLVA FPWFRWHHSL LVPHDHPLTQ
ISPLTLESIA KWPLITYRQG ITGRSRIDDA FARKGLLADI VLSAQDSDVI KTYVALGLGI
GLVAEQSSGE QEEENLIRLD TRHLFDANTV WLGLKRGQLQ RNYVWRFLEL CNAGLSVEDI
KRQVMESSEE EIDYQI
Mol. Wt

35.86 kDa (calc) [2]

pI
Extinction coefficient

36440 - 36565 (calc based on 6 Y, 5 W, and 1 C residues)

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Domains/Motifs/Modification Sites See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes

Domain

1 - 59

HTH lysR-type

UniProt:Q47083

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Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure>cbl 562</beststructure>

Models

View models at:

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:G7071-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:Q47083

UniProt (EcoliWiki Page)

UniProt:Q47083

PFAM (EcoliWiki Page)

PFAM:PF00126

RefSeq (EcoliWiki Page)

RefSeq:NP_416492

ModBase (EcoliWiki Page)

ModBase:Q47083


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Notes

Links

[back to top]


Name URL Comments
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References

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  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 4.3 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. ↑ 5.0 5.1 5.2 5.3 5.4 van Der Ploeg, JR et al. (1999) The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl. J. Biol. Chem. 274 29358-65 PubMed


Categories

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