dcuA:Gene Product(s): Difference between revisions

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[http://www.uniprot.org/keywords/KW-0397 SP_KW:KW-0397]<br />[http://www.uniprot.org/keywords/KW-0472 SP_KW:KW-0472]
[http://www.uniprot.org/keywords/KW-0397 SP_KW:KW-0397]<br />[http://www.uniprot.org/keywords/KW-0472 SP_KW:KW-0472]
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C
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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complete
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[[Category:GO:0016021_!_integral_to_membrane]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016021_!_integral_to_membrane GO:0016021]
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integral to membrane
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
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IEA: Inferred from Electronic Annotation
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[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR004668 InterPro:IPR004668]<br />[http://www.uniprot.org/keywords/KW-0812 SP_KW:KW-0812]
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C
C
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required fields missing   
required fields missing   
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[[Category:GO:0016021_!_integral_to_membrane]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016021_!_integral_to_membrane GO:0016021]
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integral to membrane
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
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IEA: Inferred from Electronic Annotation
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[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR004668 InterPro:IPR004668]<br />[http://www.uniprot.org/keywords/KW-0812 SP_KW:KW-0812]
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C
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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complete


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Revision as of 00:52, 20 November 2008

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

DcuA product

Synonyms

C4-dicarboxylate antiporter product[1], B4138 product[2][1], GenA product[2][1], DcuA product[2][1]

Product description

DcuA dicarboxylate Dcu transporter[2][3]

EC number (for enzymes)
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See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0015556

C4-dicarboxylate transmembrane transporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004668

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0015740

C4-dicarboxylate transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004668

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0016020

membrane

GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0016021

integral to membrane

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR004668
SP_KW:KW-0812

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0015292

uniporter activity

F

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0016052

carbohydrate catabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions

Partner Type Partner Notes References
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See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Notes

Localization

Compartment Description Evidence Notes

plasma membrane

C-terminus localized to the periplasm with 11 predicted transmembrane domains

Daley et al. (2005) [5]

plasma membrane

From EcoCyc[3]

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See Help:Product_localization for how to add or edit information in this section of EcoliWiki.


Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc 

MLVVELIIVL LAIFLGARLG GIGIGFAGGL GVLVLAAIGV KPGNIPFDVI SIIMAVIAAI
SAMQVAGGLD YLVHQTEKLL RRNPKYITIL APIVTYFLTI FAGTGNISLA TLPVIAEVAK
EQGVKPCRPL STAVVSAQIA ITASPISAAV VYMSSVMEGH GISYLHLLSV VIPSTLLAVL
VMSFLVTMLF NSKLSDDPIY RKRLEEGLVE LRGEKQIEIK SGAKTSVWLF LLGVVGVVIY
AIINSPSMGL VEKPLMNTTN AILIIMLSVA TLTTVICKVD TDNILNSSTF KAGMSACICI
LGVAWLGDTF VSNNIDWIKD TAGEVIQGHP WLLAVIFFFA SALLYSQAAT AKALMPMALA
LNVSPLTAVA SFAAVSGLFI LPTYPTLVAA VQMDDTGTTR IGKFVFNHPF FIPGTLGVAL
AVCFGFVLGS FML
Mol. Wt

45.75 kDa (calc) [2]

pI
Extinction coefficient

35410 - 36035 (calc based on 9 Y, 4 W, and 5 C residues)

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See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Domains/Motifs/Modification Sites

Type Residues Description Notes

Domain

162 - 184

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

226 - 243

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

258 - 277

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

284 - 306

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

326 - 345

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

358 - 380

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

410 - 432

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

130 - 152

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

50 - 72

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

87 - 109

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

15 - 37

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

tmhmm.php?gene=dcuA&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure

Structures

<beststructure>dcuA 562</beststructure>

Models

View models at:

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See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Notes

Gene Product Resources

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Resource type Source Notes/Reference
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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Notes

Accessions in Other Databases

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:DCUA-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0ABN5

PFAM (EcoliWiki Page)

PFAM:PF03605

RefSeq (EcoliWiki Page)

RefSeq:NP_418561


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See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.

Notes

Links

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Name URL Comments
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See Help:Links_table for how to enter or edit information in this section of EcoliWiki.



References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 4.3 4.4 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  6. ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed


Categories

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