maeB:Gene Product(s): Difference between revisions

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[http://www.uniprot.org/keywords/KW-0560 SP_KW:KW-0560]
[http://www.uniprot.org/keywords/KW-0560 SP_KW:KW-0560]
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F
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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complete
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[[Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor GO:0016616]
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oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]
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IEA: Inferred from Electronic Annotation
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[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012188 InterPro:IPR012188]<br />[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012301 InterPro:IPR012301]<br />[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012302 InterPro:IPR012302]
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F
F
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[[Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor GO:0016616]
[[Category:GO:0046872_!_metal_ion_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0046872_!_metal_ion_binding GO:0046872]
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oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
metal ion binding
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]
[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012188 InterPro:IPR012188]<br />[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012301 InterPro:IPR012301]<br />[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012302 InterPro:IPR012302]
[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012188 InterPro:IPR012188]<br />[http://www.uniprot.org/keywords/KW-0479 SP_KW:KW-0479]
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F
F

Revision as of 04:04, 18 November 2008

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

MaeB product

Synonyms

fused malic enzyme predicted oxidoreductase product[1], predicted phosphotransacetylase product[1], B2463 product[2][1], YpfF product[2][1], MaeB product[2][1]

Product description

MaeB[2][3];

Component of ; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P18843

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0003824

catalytic activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0511

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0004473

malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.1.1.40

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002505

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0008415

acyltransferase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002505

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0016491

oxidoreductase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0016616

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012188
InterPro:IPR012301
InterPro:IPR012302

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0006094

gluconeogenesis

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0046872

metal ion binding

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR012188
SP_KW:KW-0479

F

Seeded from EcoCyc 12.5 [5]

complete

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Interactions

Partner Type Partner Notes

Protein

Subunits of malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)

could be indirect

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See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Notes

Localization

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc 

MDDQLKQSAL DFHEFPVPGK IQVSPTKPLA TQRDLALAYS PGVAAPCLEI EKDPLKAYKY
TARGNLVAVI SNGTAVLGLG NIGALAGKPV MEGKGVLFKK FAGIDVFDIE VDELDPDKFI
EVVAALEPTF GGINLEDIKA PECFYIEQKL RERMNIPVFH DDQHGTAIIS TAAILNGLRV
VEKNISDVRM VVSGAGAAAI ACMNLLVALG LQKHNIVVCD SKGVIYQGRE PNMAETKAAY
AVVDDGKRTL DDVIEGADIF LGCSGPKVLT QEMVKKMARA PMILALANPE PEILPPLAKE
VRPDAIICTG RSDYPNQVNN VLCFPFIFRG ALDVGATAIN EEMKLAAVRA IAELAHAEQS
EVVASAYGDQ DLSFGPEYII PKPFDPRLIV KIAPAVAKAA MESGVATRPI ADFDVYIDKL
TEFVYKTNLF MKPIFSQARK APKRVVLPEG EEARVLHATQ ELVTLGLAKP ILIGRPNVIE
MRIQKLGLQI KAGVDFEIVN NESDPRFKEY WTEYFQIMKR RGVTQEQAQR ALISNPTVIG
AIMVQRGEAD AMICGTVGDY HEHFSVVKNV FGYRDGVHTA GAMNALLLPS GNTFIADTYV
NDEPDAEELA EITLMAAETV RRFGIEPRVA LLSHSNFGSS DCPSSSKMRQ ALELVRERAP
ELMIDGEMHG DAALVEAIRN DRMPDSSLKG SANILVMPNM EAARISYNLL RVSSSEGVTV
GPVLMGVAKP VHVLTPIASV RRIVNMVALA VVEAQTQPL
Mol. Wt

82.42 kDa (calc) [2]

pI
Extinction coefficient

30830 - 31955 (calc based on 17 Y, 1 W, and 9 C residues)

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See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Domains/Motifs/Modification Sites

Type Residues Description Notes
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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Structure

Structures

<beststructure>maeB 562</beststructure>

Models

View models at:

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See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:MALIC-NADP-MONOMER

UniProt (EcoliWiki Page)

UniProt:P76558

PFAM (EcoliWiki Page)

PFAM:PF00390

RefSeq (EcoliWiki Page)

RefSeq:NP_416958

ModBase (EcoliWiki Page)

ModBase:P76558


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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7


Categories

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