maeB:Gene Product(s): Difference between revisions

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!{{table heading style}} |Standard name
!align=left {{table heading style}} |Standard name
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MaeB product  
MaeB product  
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!{{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
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fused malic enzyme predicted oxidoreductase product<ref name='LIB:Riley_2006'/>, predicted phosphotransacetylase product<ref name='LIB:Riley_2006'/>, B2463 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YpfF product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MaeB product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
fused malic enzyme predicted oxidoreductase product<ref name='LIB:Riley_2006'/>, predicted phosphotransacetylase product<ref name='LIB:Riley_2006'/>, B2463 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YpfF product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MaeB product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
|-
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!{{table heading style}} |Product description
!align=left {{table heading style}} |Product description
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MaeB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
MaeB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  


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!{{table heading style}} |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
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|- {{table_heading_style}}
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|
|
[[Category:GO:0003824_!_catalytic_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003824_!_catalytic_activity GO:0003824]
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catalytic activity
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GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0511
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F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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complete
|-
|
|
[[Category:GO:0004473_!_malate_dehydrogenase_(oxaloacetate-decarboxylating)_(NADP+)_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0004473_!_malate_dehydrogenase_(oxaloacetate-decarboxylating)_(NADP+)_activity GO:0004473]
|
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
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GO_REF:0000003
|
IEA: Inferred from Electronic Annotation
|
EC:1.1.1.40
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F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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complete
|-  
|-  
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IPI: Inferred from Physical Interaction
IPI: Inferred from Physical Interaction
|
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UniProtKB:P18843
[http://www.ebi.uniprot.org/entry/P18843 UniProtKB:P18843]
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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complete
|-
|
 
|
[[Category:GO:0008152_!_metabolic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008152_!_metabolic_process GO:0008152]
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metabolic process
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GO_REF:0000002
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IEA: Inferred from Electronic Annotation
|
InterPro:IPR002505
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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complete
|-
|
 
|
[[Category:GO:0008415_!_acyltransferase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008415_!_acyltransferase_activity GO:0008415]
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acyltransferase activity
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GO_REF:0000002
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IEA: Inferred from Electronic Annotation
|
InterPro:IPR002505
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|
 
|
[[Category:GO:0016491_!_oxidoreductase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016491_!_oxidoreductase_activity GO:0016491]
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oxidoreductase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0560
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|
 
|
[[Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor GO:0016616]
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oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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GO_REF:0000002
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IEA: Inferred from Electronic Annotation
|
InterPro:IPR012188
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|
 
|
[[Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor GO:0016616]
|
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012301
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|
 
|
[[Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor GO:0016616]
|
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012302
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|
 
|
[[Category:GO:0046872_!_metal_ion_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0046872_!_metal_ion_binding GO:0046872]
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metal ion binding
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GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012188
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|
 
|
[[Category:GO:0046872_!_metal_ion_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0046872_!_metal_ion_binding GO:0046872]
|
metal ion binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0479
|
|
F
F
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required fields missing   
required fields missing   
|-
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[[Category:GO:0051287_!_NAD_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0051287_!_NAD_binding GO:0051287]
|
NAD binding
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012302
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete


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Protein
Protein
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could be indirect   
could be indirect   
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!Compartment!!Description!!Evidence!!Notes
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!{{table heading style}} |Sequence
!align=left {{table heading style}} |Sequence
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[http://biocyc.org/ECOLI/sequence-aa?object=MALIC-NADP-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=MALIC-NADP-MONOMER at EcoCyc]  
<pre>MDDQLKQSAL DFHEFPVPGK IQVSPTKPLA TQRDLALAYS PGVAAPCLEI EKDPLKAYKY
<pre>MDDQLKQSAL DFHEFPVPGK IQVSPTKPLA TQRDLALAYS PGVAAPCLEI EKDPLKAYKY
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GPVLMGVAKP VHVLTPIASV RRIVNMVALA VVEAQTQPL</pre>  
GPVLMGVAKP VHVLTPIASV RRIVNMVALA VVEAQTQPL</pre>  
|-
|-
!{{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
|
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82.42 kDa (calc) <ref name='LIB:EcoCyc10.6'/>  
82.42 kDa (calc) <ref name='LIB:EcoCyc10.6'/>  
|-
|-
!{{table heading style}} |pI
!align=left {{table heading style}} |pI
|
||
   
   
|-
|-
!{{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
|
||
30830 - 31955 (calc based on 17 Y, 1 W, and 9 C residues)  
30830 - 31955 (calc based on 17 Y, 1 W, and 9 C residues)  
|-
 
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!Database!!Accession!!Notes
!|Database!!Accession!!Notes
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[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
|
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=MALIC-NADP-MONOMER EcoCyc:MALIC-NADP-MONOMER]
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=MALIC-NADP-MONOMER EcoCyc:MALIC-NADP-MONOMER]
|
|
   
   
|-
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[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])  
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])  
|
|
[[uniprot:P76558|UniProt:P76558]]
[[uniprot:P76558|UniProt:P76558]]
|
|
   
   
|-
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[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])  
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])  
|
|
[http://pfam.sanger.ac.uk/family?acc=PF00390 PFAM:PF00390]
[http://pfam.sanger.ac.uk/family?acc=PF00390 PFAM:PF00390]
|
|
   
   
|-
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[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])  
|
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_416958 RefSeq:NP_416958]
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_416958 RefSeq:NP_416958]
|
|
   
   
|-
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|
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[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])  
[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])  
|
|
[http://salilab.org/modbase/searchbyid?databaseID=P76558 ModBase:P76558]
[http://salilab.org/modbase/searchbyid?databaseID=P76558 ModBase:P76558]
|
|
   
   
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Revision as of 02:12, 15 November 2008

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

MaeB product

Synonyms

fused malic enzyme predicted oxidoreductase product[1], predicted phosphotransacetylase product[1], B2463 product[2][1], YpfF product[2][1], MaeB product[2][1]

Product description

MaeB[2][3];

Component of ; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)[2][3]

EC number (for enzymes)
edit table

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P18843

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0006094

gluconeogenesis

P

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions

Partner Type Partner Notes

Protein

Subunits of malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)

could be indirect

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Notes

Localization

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc 

MDDQLKQSAL DFHEFPVPGK IQVSPTKPLA TQRDLALAYS PGVAAPCLEI EKDPLKAYKY
TARGNLVAVI SNGTAVLGLG NIGALAGKPV MEGKGVLFKK FAGIDVFDIE VDELDPDKFI
EVVAALEPTF GGINLEDIKA PECFYIEQKL RERMNIPVFH DDQHGTAIIS TAAILNGLRV
VEKNISDVRM VVSGAGAAAI ACMNLLVALG LQKHNIVVCD SKGVIYQGRE PNMAETKAAY
AVVDDGKRTL DDVIEGADIF LGCSGPKVLT QEMVKKMARA PMILALANPE PEILPPLAKE
VRPDAIICTG RSDYPNQVNN VLCFPFIFRG ALDVGATAIN EEMKLAAVRA IAELAHAEQS
EVVASAYGDQ DLSFGPEYII PKPFDPRLIV KIAPAVAKAA MESGVATRPI ADFDVYIDKL
TEFVYKTNLF MKPIFSQARK APKRVVLPEG EEARVLHATQ ELVTLGLAKP ILIGRPNVIE
MRIQKLGLQI KAGVDFEIVN NESDPRFKEY WTEYFQIMKR RGVTQEQAQR ALISNPTVIG
AIMVQRGEAD AMICGTVGDY HEHFSVVKNV FGYRDGVHTA GAMNALLLPS GNTFIADTYV
NDEPDAEELA EITLMAAETV RRFGIEPRVA LLSHSNFGSS DCPSSSKMRQ ALELVRERAP
ELMIDGEMHG DAALVEAIRN DRMPDSSLKG SANILVMPNM EAARISYNLL RVSSSEGVTV
GPVLMGVAKP VHVLTPIASV RRIVNMVALA VVEAQTQPL
Mol. Wt

82.42 kDa (calc) [2]

pI
Extinction coefficient

30830 - 31955 (calc based on 17 Y, 1 W, and 9 C residues)

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Domains/Motifs/Modification Sites

Type Residues Description Notes
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Structure

Structures

<beststructure>maeB 562</beststructure>

Models

View models at:

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Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:MALIC-NADP-MONOMER

UniProt (EcoliWiki Page)

UniProt:P76558

PFAM (EcoliWiki Page)

PFAM:PF00390

RefSeq (EcoliWiki Page)

RefSeq:NP_416958

ModBase (EcoliWiki Page)

ModBase:P76558


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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  5. ↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7


Categories

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