livJ:Quickview: Difference between revisions

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Repressed by L-leucine via the global transcription factor lrp.


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Revision as of 17:54, 17 July 2008

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

livJ (synonyms: ECK3444, b3460, JW3425, hrbB, hrbC, hrbD)[1]

Product(s)

LivJ product[1]: leucine/isoleucine/valine transporter subunit product, periplasmic-binding component of ABC superfamily product, B3460 product, HrbC product, HrbD product, HrbB product

Description

LivJ[2][3]

Component of branched chain amino acids ABC transporter[2]

Knock-Out Phenotype

Resistant to low levels L-valine (0.4 micromolar) on glucose minimal medium; lacks the LIV-1 high affinity leucine/valine/isoleucine uptake system; lacks the leucine/valine/isoleucine binding protein. [4]

Regulation/Expression

transcription unit(s): livJ[2], OP00255

Regulation/Activity

Repressed by L-leucine via the global transcription factor lrp.

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Notes

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References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ Anderson, JJ & Oxender, DL (1977) Escherichia coli transport mutants lacking binding protein and other components of the branched-chain amino acid transport systems. J. Bacteriol. 130 384-92 PubMed