livJ:Quickview

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Standard Name

livJ

Gene Synonym(s)

ECK3444, b3460, JW3425, hrbB, hrbC, hrbD[1], hrbD

Product Desc.

LivJ[2][3];

Component of branched chain amino acids ABC transporter[2][3]

Leu/Ile/Val-binding protein, periplasmic, high-affinity transport; LIV-I system; also involved in phenylalanine accumulation[4]

Product Synonyms(s)

leucine/isoleucine/valine transporter subunit[1], periplasmic-binding component of ABC superfamily[1], B3460[2][1], HrbC[2][1], HrbD[2][1], HrbB[2][1], LivJ[2][1] , ECK3444, hrbB, hrbC, hrbD, JW3425, b3460

Function from GO

<GO_nr />

Knock-Out Phenotype

Resistant to low levels L-valine (0.4 micromolar) on glucose minimal medium; lacks the LIV-1 high affinity leucine/valine/isoleucine uptake system; lacks the leucine/valine/isoleucine binding protein. [5]

Regulation/Expression

transcription unit(s): livJ[2], OP00255

Regulation/Activity

Repressed by L-leucine via the global transcription factor lrp.

Quick Links

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Notes

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After four hours of Zn(II) stress, LivJ protein levels decreased (Easton, 2006).[4]



References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Anderson, JJ & Oxender, DL (1977) Escherichia coli transport mutants lacking binding protein and other components of the branched-chain amino acid transport systems. J. Bacteriol. 130 384-92 PubMed