dadX:Quickview: Difference between revisions

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!{{table_heading_style}} |Knock-Out Phenotype
!{{table_heading_style}} |Knock-Out Phenotype
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ΔdadX fails to grow on L-alanine as sole carbon source. No D-alanine auxotrophy except in the double ΔalrΔdadX mutant. Either Alr or DadX supplies sufficient D-alanine for cell wall biosynthesis.
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!{{table_heading_style}} |Regulation/Expression
!{{table_heading_style}} |Regulation/Expression
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!{{table_heading_style}} |Regulation/Activity
!{{table_heading_style}} |Regulation/Activity
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Induced by L-alanine. Converts L- to D-alanine for catabolism.
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Revision as of 19:05, 9 August 2007

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

dadX (synonyms: ECK1178, b1190, JW1179, alnA, alnB, dadB, msuA?)[1][2]

Product(s)

DadX product[1]: alanine racemase 2, PLP-binding product, B1190 product, DadB product, AlnB product, AlnA product, alanine racemase product

Description

ALARACECAT-MONOMER[2][3]

Component of alanine racemase 2, PLP-binding[3]

Knock-Out Phenotype

ΔdadX fails to grow on L-alanine as sole carbon source. No D-alanine auxotrophy except in the double ΔalrΔdadX mutant. Either Alr or DadX supplies sufficient D-alanine for cell wall biosynthesis.

Regulation/Expression

transcription unit(s): dadAX[2], dad

Regulation/Activity

Induced by L-alanine. Converts L- to D-alanine for catabolism.

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Notes

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References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7