Phage PRD1: Difference between revisions

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Revision as of 16:18, 11 June 2013

This page is currently under construction, and much of the information is currently just a placeholder- it may not apply to PRD1 at all.


Bacteriophage PRD1 is closely related to the other lipid-containing phages PR3, PR4, PR5, and L17.[1]

The full sequence is available from NCBI as NCBI Reference Sequence: NC_001421.2


Morphology

Genome Organization

159192286 on NCBI


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PRD1 has a linear, 14927 bp genome of DNA.

There are 11 genes encoded on the genome; two are overlapping in-frame genes. Five of the encoded proteins make up the viron, three are needed for synthesis and the rest are for assembly. [2] The genes are generally referred to by Roman numerals I-XI as listed on the Phage f1 page. Genes are in the order II (X), V, VII, IX, VIII, III, VI, I (XI), IV, intergenic region (IG or IGR). [3] The IGR contains the packing signal (PS) as well as sequences that dictate termination, nicking for replication, and the binding of protein II and IHF. [3]

Life cycle

Adsorption and Injection

DNA replication

Packaging

Lysis

See also

References

See Help:References for how to manage references in EcoliWiki.

  1. ↑ Bamford, DH et al. (1981) Comparison of the lipid-containing bacteriophages PRD1, PR3, PR4, PR5 and L17. J. Gen. Virol. 57 365-73 PubMed
  2. ↑ Russel, M et al. (1997) Filamentous phage assembly: variation on a protein export theme. Gene 192 23-32 PubMed
  3. ↑ 3.0 3.1 Edited by Richard Calendar (2006) The Bacteriophages (Oxford University Press, Oxford, NY) ISBN 0-19-514850-9