ftsK:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK0881, b0890, JW0873, dinH''<ref name='LIB:Riley_2006'/>, dinH''
''ECK0881, b0890, JW0873, dinH''<ref name='LIB:Riley_2006'/>, dinH'',
usoM <ref name='PMID:9294449'/>
usoM <ref name='PMID:9294449'/>
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Revision as of 19:30, 14 November 2011

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

ftsK

Gene Synonym(s)

ECK0881, b0890, JW0873, dinH[1], dinH, usoM [2]

Product Desc.

essential cell division protein FtsK [3][4][5];

Component of Xer site-specific recombination system[5]

DNA translocase at septal ring sorting daughter chromsomes[6]

Product Synonyms(s)

DNA-binding membrane protein required for chromosome resolution and partitioning[1], B0890[4][1], DinH[4][1], FtsK[4][1]

Function from GO

<GO_nr />

Knock-Out Phenotype

ts mutants filament

Regulation/Expression

transcription unit(s): ftsK[4], dinH

Regulation/Activity
Quick Links

PortEco search(ftsK)    DNA display    Protein display    Pubmed(ftsK)    Textpresso(ftsK)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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FtsK is required for resolution of chromosome dimers at dif by XerCD. FtsK helps keep the nucleoids properly localized, recognizing opposing replichores by using FtsK orienting polar sequences (KOPS). The N-terminal domain is membrane-anchored, localizes to the division septum and is required for cell division. The C-terminal domain has the non-essential translocase activity, which becomes essential for replicating the asymmetric replichores produced by chromosome inversion (Lesterlin, 2008). LexA regulon. Homologous to B. subtilis SpoIIIE protein. The ftsK gene is essential. The filamentous growth of mutants is suppressed by dacA deletions. ftsK44(ts) can be suppressed by an ftsA R286W mutation or by an ftsQAZ plasmid. Divisome.[6]



References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ Arnau, J et al. (1997) Cloning, expression, and characterization of the Lactococcus lactis pfl gene, encoding pyruvate formate-lyase. J. Bacteriol. 179 5884-91 PubMed
  3. ↑ Wang, L & Lutkenhaus, J (1998) FtsK is an essential cell division protein that is localized to the septum and induced as part of the SOS response. Mol. Microbiol. 29 731-40 PubMed
  4. ↑ 4.0 4.1 4.2 4.3 4.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. ↑ 5.0 5.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. ↑ 6.0 6.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.