thyA:Quickview: Difference between revisions

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[http://porteco.org/AjaxSearch.jsp?searchString=thyA&s=search PortEco search(thyA)]    [http://ecoliwiki.net/tools/display_dna.php?gene=thyA&loc=MG1655:2963177..2962383,W3110:2963811..2963017,REL606:2859775..2858981,DH10B:3057047..3056253,BW2952:2849531..2850325 DNA display]    [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2849531&end=2850325&gene=thyA&aa=mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihellwflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlkndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfniasyallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesifdyrfedfeiegydphpgikapvai Protein display]    [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=thyA+AND+escherichia+coli Pubmed(thyA)]    [http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=thyA Textpresso(thyA)]
[http://porteco.org/AjaxSearch.jsp?searchString=thyA&s=search PortEco search(thyA)]    [http://ecoliwiki.net/tools/display_dna.php?gene=thyA&loc=MG1655:2963177..2962383,W3110:2963811..2963017,REL606:2859775..2858981,DH10B:3057047..3056253,BW2952:2849531..2850325 DNA display]    [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2849531&end=2850325&gene=thyA&aa= Protein display]    [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=thyA+AND+escherichia+coli Pubmed(thyA)]    [http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=thyA Textpresso(thyA)]


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Revision as of 19:46, 16 August 2011

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

thyA

Gene Synonym(s)

ECK2823, b2827, JW2795[1]

Product Desc.

thymidylate synthase[2][3];

Component of thymidylate synthase[2][3]

Thymidylate synthase; aminopterin, trimethoprim resistance; homodimer[4]

Product Synonyms(s)

thymidylate synthetase[1], B2827[2][1], ThyA[2][1], 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): lgt-thyA[2]

Regulation/Activity
Quick Links

PortEco search(thyA)    DNA display    Protein display    Pubmed(thyA)    Textpresso(thyA)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Thymidylate synthase (TS) catalytic mechanism order: TS + dUMP --> TS x dUMP + (6R)-5,10-CH2-H4folate --> TS x dUMP x (6R)-5,10-CH2H4folate --> TS x dTMP x H2folate --> TS x dTMP --> TS.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.