mhpE:Gene Product(s): Difference between revisions

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|-
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!align=left |Standard name
!align=left {{table heading style}} |Standard name
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MhpE  
MhpE  
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!align=left |Synonyms
!align=left {{table heading style}} |Synonyms
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4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase, class I<ref name='LIB:Riley_2006'/>, B0352<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MhpE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase, class I<ref name='LIB:Riley_2006'/>, B0352<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MhpE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Product description
!align=left {{table heading style}} |Product description
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4-Hydroxy-2-oxovalerate aldolase; utilizes MHP<ref name='LIB:EcoGene'/>
4-Hydroxy-2-oxovalerate aldolase; utilizes MHP<ref name='LIB:EcoGene'/>
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!align=left |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
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* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.- 4.1.3.-]<ref name='LIB:Riley_2006'/>
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.- 4.1.3.-]<ref name='LIB:Riley_2006'/>
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****************************************************************************************** -->{{Product_GO_help}}
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{|  id="G46aa2a9cc0122"  class=" tableEdit GO_table_product dataTable"   
{|  id="G46aa2a9cc0122"  class=" tableEdit GO_table_product dataTable"   
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|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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*  
*  
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{|  id="T46aa2aa3b1595"  class=" tableEdit Product_interactions_table"   
{|  id="T46aa2aa3b1595"  class=" tableEdit Product_interactions_table dataTable"   
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|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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{|  id="K46a7bbe6753f8"  class=" tableEdit Product_localization_table"   
{|  id="K46a7bbe6753f8"  class=" tableEdit Product_localization_table"   
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!|Compartment!!Description!!Evidence!!Source!!Notes
!|Compartment!!Description!!Evidence!!Source!!Notes


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|-
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!align=left |Sequence
!align=left {{table heading style}} |Sequence
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[http://biocyc.org/ECOLI/sequence-aa?object=MHPELY-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=MHPELY-MONOMER at EcoCyc]  
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RYGLSAVDIL VELGKRRMVG GQEDMIVDVA LDLRNNK</pre>  
RYGLSAVDIL VELGKRRMVG GQEDMIVDVA LDLRNNK</pre>  
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!align=left |Length
!align=left {{table heading style}} |Length
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337
337
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!align=left |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
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36.47 kDa
36.47 kDa
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!align=left |pI
!align=left {{table heading style}} |pI
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6.0 (calculated)
6.0 (calculated)
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!align=left |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
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31,400 - 31,900 (calc based on 10 Y, 3 W, and 4 C residues)
31,400 - 31,900 (calc based on 10 Y, 3 W, and 4 C residues)
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*  
****************************************************************************************** -->{{Product_domains_motifs_help}}
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{|  id="I46aa2aa5c788b"  class=" tableEdit Product_motif_table"   
{|  id="I46aa2aa5c788b"  class=" tableEdit Product_motif_table dataTable"   
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!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References


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|-
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!align=left |Structures
!align=left {{table heading style}} |Structures
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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left |Models
!align=left {{table heading style}} |Models
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View models at:
View models at:
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{|  id="P46aa2aa6679a8"  class=" tableEdit Product_resource_table"   
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!|Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference


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{|  id="T46aa2aa6b16ee"  class=" tableEdit Gene_accessions_table"   
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!|Database!!Accession!!Notes
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!|Name!!URL!!Comments
!|Name!!URL!!Comments


Revision as of 20:27, 23 February 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MhpE

Synonyms

4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase, class I[1], B0352[2][1], MhpE[2][1]

Product description

4-Hydroxy-2-oxovalerate aldolase; utilizes MHP[3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0003824

catalytic activity

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000891
InterPro:IPR013785

F

Seeded from EcoCyc [4]

complete

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013785

P

Seeded from EcoCyc [4]

complete

GO:0016829

lyase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0456

F

Seeded from EcoCyc [4]

complete

GO:0016833

oxo-acid-lyase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012425

F

Seeded from EcoCyc [4]

complete

GO:0019439

aromatic compound catabolic process

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR012425
SP_KW:KW-0058

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

required fields missing

GO:0008701

4-hydroxy-2-oxovalerate aldolase activity

GO_REF:0000020
GO_REF:0000002
GO_REF:0000003

IEA: Inferred from Electronic Annotation

HAMAP:MF_01656
InterPro:IPR017629
EC:4.1.3.39

F

Seeded from EcoCyc [4]

complete

GO:0019395

fatty acid oxidation

P

Seeded from EcoCyc 11.1[6].

required fields missing

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

glpD

PMID:16606699[7]

Experiment(s):EBI-1136343

Protein

prs

PMID:16606699[7]

Experiment(s):EBI-1136343

Protein

mlc

PMID:16606699[7]

Experiment(s):EBI-1136343

Protein

uspG

PMID:16606699[7]

Experiment(s):EBI-1136343

Protein

fdnH

PMID:16606699[7]

Experiment(s):EBI-1136343

Protein

rsuA

PMID:16606699[7]

Experiment(s):EBI-1136343

Protein

rplN

PMID:16606699[7]

Experiment(s):EBI-1136343

Protein

groL

PMID:16606699[7]

Experiment(s):EBI-1136343
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MNGKKLYISD VTLRDGMHAI RHQYSLENVR QIAKALDDAR VDSIEVAHGD GLQGSSFNYG
FGAHSDLEWI EAAADVVKHA KIATLLLPGI GTIHDLKNAW QAGARVVRVA THCTEADVSA
QHIQYARELG MDTVGFLMMS HMTTPENLAK QAKLMEGYGA TCIYVVDSGG AMNMSDIRDR
FRALKAELKP ETQTGMHAHH NLSLGVANSI AAVEEGCDRI DASLAGMGAG AGNAPLEVFI
AAADKLGWQH GTDLYALMDA ADDLVRPLQD RPVRVDRETL ALGYAGVYSS FLRHCETAAA
RYGLSAVDIL VELGKRRMVG GQEDMIVDVA LDLRNNK
Length

337

Mol. Wt

36.47 kDa

pI

6.0 (calculated)

Extinction coefficient

31,400 - 31,900 (calc based on 10 Y, 3 W, and 4 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=mhpE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:MHPELY-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:P51020

UniProt (EcoliWiki Page)

UniProt:P51020

PFAM (EcoliWiki Page)

PFAM:PF00682

RefSeq (EcoliWiki Page)

RefSeq:NP_414886


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. ↑ 4.0 4.1 4.2 4.3 4.4 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  5. ↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

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