adiC:Gene Product(s): Difference between revisions

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|-
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!align=left |Standard name
!align=left {{table heading style}} |Standard name
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AdiC  
AdiC  
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!align=left |Synonyms
!align=left {{table heading style}} |Synonyms
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arginine:agmatin<ref name='LIB:Riley_2006'/>, B4115 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjdD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjdE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AdiC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
arginine:agmatin<ref name='LIB:Riley_2006'/>, B4115 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjdD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjdE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AdiC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Product description
!align=left {{table heading style}} |Product description
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AdiC Arginine:Agmatine Antiporter<ref name='LIB:EcoCyc10.6'/>; AdiC<ref name='LIB:EcoCyc11.1'/>;  
AdiC Arginine:Agmatine Antiporter<ref name='LIB:EcoCyc10.6'/>; AdiC<ref name='LIB:EcoCyc11.1'/>;  
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Arginine:agmatine antiporter; arginine-dependent acid resistance; acid-inducible membrane protein<ref name='LIB:EcoGene'/>
Arginine:agmatine antiporter; arginine-dependent acid resistance; acid-inducible membrane protein<ref name='LIB:EcoGene'/>
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!align=left |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
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****************************************************************************************** -->{{Product_GO_help}}
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{|  id="X46ab1dac253d1"  class=" tableEdit GO_table_product dataTable"   
{|  id="X46ab1dac253d1"  class=" tableEdit GO_table_product dataTable"   
|-
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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*  
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{|  id="P46ab1db792b9b"  class=" tableEdit Product_interactions_table"   
{|  id="P46ab1db792b9b"  class=" tableEdit Product_interactions_table dataTable"   
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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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{|  id="N46ab1db8df4e3"  class=" tableEdit Product_localization_table"   
{|  id="N46ab1db8df4e3"  class=" tableEdit Product_localization_table"   
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!|Compartment!!Description!!Evidence!!Source!!Notes
!|Compartment!!Description!!Evidence!!Source!!Notes
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|-
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!align=left |Sequence
!align=left {{table heading style}} |Sequence
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[http://biocyc.org/ECOLI/sequence-aa?object=YJDE-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=YJDE-MONOMER at EcoCyc]  
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TAMYALNYNR LHKNPYPLDA PISKD</pre>  
TAMYALNYNR LHKNPYPLDA PISKD</pre>  
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!align=left |Length
!align=left {{table heading style}} |Length
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445
445
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!align=left |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
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46.843 kDa
46.843 kDa
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!align=left |pI
!align=left {{table heading style}} |pI
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9.0 (calculated)
9.0 (calculated)
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!align=left |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
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85,830 - 86,830 (calc based on 17 Y, 11 W, and 8 C residues)
85,830 - 86,830 (calc based on 17 Y, 11 W, and 8 C residues)
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*  
*  
****************************************************************************************** -->{{Product_domains_motifs_help}}
****************************************************************************************** -->{{Product_domains_motifs_help}}
{|  id="L46ab1dbb95713"  class=" tableEdit Product_motif_table"   
{|  id="L46ab1dbb95713"  class=" tableEdit Product_motif_table dataTable"   
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|- {{table heading style}}
!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References


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|-
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!align=left |Structures
!align=left {{table heading style}} |Structures
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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left |Models
!align=left {{table heading style}} |Models
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View models at:
View models at:
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****************************************************************************************** -->{{Product_resources_help}}
****************************************************************************************** -->{{Product_resources_help}}
{|  id="E46ab1dbc6c40d"  class=" tableEdit Product_resource_table"   
{|  id="E46ab1dbc6c40d"  class=" tableEdit Product_resource_table"   
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!|Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference


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{|  id="R46ab1dbcd1153"  class=" tableEdit Gene_accessions_table"   
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!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
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{|  id="N46ab1dbfb5c85"  class=" tableEdit Links_table"   
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!|Name!!URL!!Comments
!|Name!!URL!!Comments


Revision as of 19:19, 23 February 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

AdiC

Synonyms

arginine:agmatin[1], B4115 product[2][1], YjdD[2][1], YjdE[2][1], AdiC[2][1]

Product description

AdiC Arginine:Agmatine Antiporter[2]; AdiC[3];

Component of AdiC arginine:agmatine antiporter[3]

Arginine:agmatine antiporter; arginine-dependent acid resistance; acid-inducible membrane protein[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0001101

response to acid

PMID:12867448[5]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc [6]

complete

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc [6]

complete

GO:0016020

membrane

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR002293
InterPro:IPR004841
SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [7]

complete

GO:0015171

amino acid transmembrane transporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002293

F

Seeded from EcoCyc [6]

complete

GO:0006865

amino acid transport

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR002293
SP_KW:KW-0029

P

Seeded from EcoCyc [6]

complete

GO:0006810

transport

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR004841
SP_KW:KW-0813

P

Seeded from EcoCyc [6]

complete

GO:0015300

solute:solute antiporter activity

PMID:17099215[8]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc [6]

complete

GO:0051454

intracellular pH elevation

PMID:12867448[5]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc [6]

complete

GO:0015292

uniporter activity

F

Seeded from EcoCyc 10.6[2].

required fields missing

GO:0005886

plasma membrane

GO_REF:0000004
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997
SP_KW:KW-1003
SP_SL:SL-0037

C

Seeded from EcoCyc [6]

complete

GO:0015297

antiporter activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0050

F

Seeded from EcoCyc [6]

complete

GO:0051454

intracellular pH elevation

PMID:12867448[5]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc 11.1[3].

complete

GO:0015300

solute:solute antiporter activity

PMID:17099215[8]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 11.1[3].

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of AdiC arginine:agmatine antiporter

could be indirect


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 11 predicted transmembrane domains

Daley et al. (2005) [9]

plasma membrane

From EcoCyc[3]


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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MSSDADAHKV GLIPVTLMVS GNIMGSGVFL LPANLASTGG IAIYGWLVTI IGALGLSMVY
AKMSFLDPSP GGSYAYARRC FGPFLGYQTN VLYWLACWIG NIAMVVIGVG YLSYFFPILK
DPLVLTITCV VVLWIFVLLN IVGPKMITRV QAVATVLALI PIVGIAVFGW FWFRGETYMA
AWNVSGLGTF GAIQSTLNVT LWSFIGVESA SVAAGVVKNP KRNVPIATIG GVLIAAVCYV
LSTTAIMGMI PNAALRVSAS PFGDAARMAL GDTAGAIVSF CAAAGCLGSL GGWTLLAGQT
AKAAADDGLF PPIFARVNKA GTPVAGLIIV GILMTIFQLS SISPNATKEF GLVSSVSVIF
TLVPYLYTCA ALLLLGHGHF GKARPAYLAV TTIAFLYCIW AVVGSGAKEV MWSFVTLMVI
TAMYALNYNR LHKNPYPLDA PISKD
Length

445

Mol. Wt

46.843 kDa

pI

9.0 (calculated)

Extinction coefficient

85,830 - 86,830 (calc based on 17 Y, 11 W, and 8 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References
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<motif_map/>

tmhmm.php?gene=adiC&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=adiC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:YJDE-MONOMER

UniProt (EcoliWiki Page)

UniProt:P60061

PFAM (EcoliWiki Page)

PFAM:PF00324

RefSeq (EcoliWiki Page)

RefSeq:NP_418539


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 Gong, S et al. (2003) YjdE (AdiC) is the arginine:agmatine antiporter essential for arginine-dependent acid resistance in Escherichia coli. J. Bacteriol. 185 4402-9 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 6.8 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  7. ↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  8. ↑ 8.0 8.1 Fang, Y et al. (2007) A bacterial arginine-agmatine exchange transporter involved in extreme acid resistance. J Biol Chem 282 176-82 PubMed
  9. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed

Categories

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