mtn:Gene Product(s): Difference between revisions

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!align=left |Standard name
!align=left {{table heading style}} |Standard name
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Pfs  
Pfs  
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!align=left |Synonyms
!align=left {{table heading style}} |Synonyms
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5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase<ref name='LIB:Riley_2006'/>, B0159<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mtn<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YadA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Pfs<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase<ref name='LIB:Riley_2006'/>, B0159<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mtn<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YadA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Pfs<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Product description
!align=left {{table heading style}} |Product description
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5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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5'-Methylthioadenosine nucleosidase; S-adenosylhomocysteine and 5'-deoxyadenosine are also substrates<ref name='LIB:EcoGene'/>
5'-Methylthioadenosine nucleosidase; S-adenosylhomocysteine and 5'-deoxyadenosine are also substrates<ref name='LIB:EcoGene'/>
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!align=left |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
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  [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9]<ref name='LIB:Riley_2006'/>
  [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9]<ref name='LIB:Riley_2006'/>
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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GO:0019509
GO:0019509
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methionine salvage
L-methionine salvage from methylthioadenosine
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GO_REF:0000002
GO_REF:0000002
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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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!|Compartment!!Description!!Evidence!!Source!!Notes
!|Compartment!!Description!!Evidence!!Source!!Notes


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!align=left |Sequence
!align=left {{table heading style}} |Sequence
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[http://biocyc.org/ECOLI/sequence-aa?object=EG11090-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=EG11090-MONOMER at EcoCyc]  
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VCHNFNVPFV VVRAISDVAD QQSHLSFDEF LAVAAKQSSL MVESLVQKLA HG</pre>  
VCHNFNVPFV VVRAISDVAD QQSHLSFDEF LAVAAKQSSL MVESLVQKLA HG</pre>  
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!align=left |Length
!align=left {{table heading style}} |Length
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232
232
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232
232
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!align=left |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
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24.353 kDa
24.353 kDa
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24.353 kDa
24.353 kDa
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!align=left |pI
!align=left {{table heading style}} |pI
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4.9 (calculated)
4.9 (calculated)
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4.9 (calculated)
4.9 (calculated)
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!align=left |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
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5,960 - 6,585 (calc based on 4 Y,  W, and 5 C residues)
5,960 - 6,585 (calc based on 4 Y,  W, and 5 C residues)
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!|Type!!Residues!!Description!!Notes
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!align=left |Structures
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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left |Models
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View models at:
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Revision as of 22:39, 3 February 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Pfs

Synonyms

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase[1], B0159[2][1], Mtn[2][1], YadA[2][1], Pfs[2][1]

Product description

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase[2][3];

Component of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase[3]

5'-Methylthioadenosine nucleosidase; S-adenosylhomocysteine and 5'-deoxyadenosine are also substrates[4]

EC number (for enzymes) 
3.2.2.9[1]
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

PMID:16858726[5]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc [6]

complete

GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000845

F

Seeded from EcoCyc [6]

complete

GO:0008782

adenosylhomocysteine nucleosidase activity

GO_REF:0000002
GO_REF:0000003

IEA: Inferred from Electronic Annotation

InterPro:IPR010049
EC:3.2.2.9

F

Seeded from EcoCyc [6]

complete

GO:0008930

methylthioadenosine nucleosidase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010049

F

Seeded from EcoCyc [6]

complete

GO:0009116

nucleoside metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000845

P

Seeded from EcoCyc [6]

complete

GO:0009164

nucleoside catabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010049

P

Seeded from EcoCyc [6]

complete

GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded from EcoCyc [6]

complete

GO:0019509

L-methionine salvage from methylthioadenosine

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010049

P

Seeded from EcoCyc [6]

complete

GO:0015949

nucleobase, nucleoside and nucleotide interconversion

P

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

could be indirect

Protein

Subunits of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

could be indirect


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MKIGIIGAME EEVTLLRDKI ENRQTISLGG CEIYTGQLNG TEVALLKSGI GKVAAALGAT
LLLEHCKPDV IINTGSAGGL APTLKVGDIV VSDEARYHDA DVTAFGYEYG QLPGCPAGFK
ADDKLIAAAE ACIAELNLNA VRGLIVSGDA FINGSVGLAK IRHNFPQAIA VEMEATAIAH
VCHNFNVPFV VVRAISDVAD QQSHLSFDEF LAVAAKQSSL MVESLVQKLA HG

at EcoCyc 

MKIGIIGAME EEVTLLRDKI ENRQTISLGG CEIYTGQLNG TEVALLKSGI GKVAAALGAT
LLLEHCKPDV IINTGSAGGL APTLKVGDIV VSDEARYHDA DVTAFGYEYG QLPGCPAGFK
ADDKLIAAAE ACIAELNLNA VRGLIVSGDA FINGSVGLAK IRHNFPQAIA VEMEATAIAH
VCHNFNVPFV VVRAISDVAD QQSHLSFDEF LAVAAKQSSL MVESLVQKLA HG
Length

232

232

Mol. Wt

24.353 kDa

24.353 kDa

pI

4.9 (calculated)

4.9 (calculated)

Extinction coefficient

5,960 - 6,585 (calc based on 4 Y, W, and 5 C residues)

5,960 - 6,585 (calc based on 4 Y, W, and 5 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=mtn taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11090-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:P0AF12

UniProt (EcoliWiki Page)

UniProt:P0AF12

PFAM (EcoliWiki Page)

PFAM:PF01048

RefSeq (EcoliWiki Page)

RefSeq:NP_414701


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70

Categories

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