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!align=left {{table_heading_style}} |Function from GO
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype

Revision as of 19:35, 2 February 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

marA

Gene Synonym(s)

ECK1524, b1531, JW5249, cfxB, norB, soxQ, inaR, nfxC[1]

Product Desc.

MarA transcriptional activator[2]; MarA transcriptional dual regulator[3]

Transcriptional activator for multiple antibiotic resistance; AraC family; resistance to tetracycline, chloramphenicol[4]

Product Synonyms(s)

DNA-binding transcriptional dual activator of multiple antibiotic resistance[1], B1531[2][1], CfxB[2][1], InaR[2][1], NorB[2][1], SoxQ[2][1], NfxC[2][1], MarA[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): marRAB[2], OP00264

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(marA)    Textpresso(marA)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Martin (2002) provide some evidence in support of the this alternative ATG start: native protein is slightly smaller than the engineered protein by Western blot. The spacing to the GAGG RBS is bad for the first ATG and excellent for the second ATG. MarA is unstable.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.