cspE:Quickview: Difference between revisions
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!align=left | !align=left {{table_heading_style}} |Standard Name | ||
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''cspE'' | ''cspE'' | ||
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!align=left | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK0616, b0623, JW0618, gicA, msmC''<ref name='LIB:Riley_2006'/> | ''ECK0616, b0623, JW0618, gicA, msmC''<ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Desc. | ||
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cold shock protein CspE<ref name='LIB:EcoCyc10.6'/>; transcription antiterminator and regulator of RNA stability<ref name='LIB:EcoCyc11.1'/> | cold shock protein CspE<ref name='LIB:EcoCyc10.6'/>; transcription antiterminator and regulator of RNA stability<ref name='LIB:EcoCyc11.1'/> | ||
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Binds and melts RNA, involved in cold acclimation; binds ssDNA; high copy protects the chromosome from decondensation by camphor and increases DNA supercoiling; dimeric<ref name='LIB:EcoGene'/> | Binds and melts RNA, involved in cold acclimation; binds ssDNA; high copy protects the chromosome from decondensation by camphor and increases DNA supercoiling; dimeric<ref name='LIB:EcoGene'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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DNA-binding transcriptional repressor<ref name='LIB:Riley_2006'/>, B0623<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsmC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GicA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CspE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | DNA-binding transcriptional repressor<ref name='LIB:Riley_2006'/>, B0623<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsmC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GicA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CspE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Function from GO | ||
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'''Molecular Function''' | |||
* GO:0003697 single-stranded DNA binding ([http://www.geneontology.org/GO.evidence.shtml IDA]) | |||
* GO:0008143 poly(A) RNA binding ([http://www.geneontology.org/GO.evidence.shtml IDA]) | |||
* GO:0030401 transcription antiterminator activity ([http://www.geneontology.org/GO.evidence.shtml IDA]) | |||
'''Biological Process''' | |||
* GO:0060567 negative regulation of transcription termination ([http://www.geneontology.org/GO.evidence.shtml IDA]) | |||
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!align=left | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | |||
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transcription unit(s): [[:Category:Txn_unit:cspE|cspE]]<ref name='LIB:EcoCyc10.6'/> | transcription unit(s): [[:Category:Txn_unit:cspE|cspE]]<ref name='LIB:EcoCyc10.6'/> | ||
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!align=left | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[http://ecoliwiki.net/tools/display_dna.php?gene=cspE&loc=MG1655:656515..656724,W3110:657714..657923,DH10B:595847..596056,DH10B:709107..709316,REL606:639873..640082 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=639873&end=640082&gene=cspE&aa=mskikgnvkwfneskgfgfitpedgskdvfvhfsaiqtngfktlaegqrvefeitngakgpsaanvial Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=cspE+AND+escherichia+coli Pubmed(cspE)] [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=cspE Textpresso(cspE)] | |||
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Revision as of 00:06, 22 January 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
cspE |
|---|---|
| Gene Synonym(s) |
ECK0616, b0623, JW0618, gicA, msmC[1] |
| Product Desc. |
cold shock protein CspE[2]; transcription antiterminator and regulator of RNA stability[3] Binds and melts RNA, involved in cold acclimation; binds ssDNA; high copy protects the chromosome from decondensation by camphor and increases DNA supercoiling; dimeric[4] |
| Product Synonyms(s) |
DNA-binding transcriptional repressor[1], B0623[2][1], MsmC[2][1], GicA[2][1], CspE[2][1] |
| Function from GO |
Molecular Function
Biological Process
|
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
The cspABEG deletion BX04 is cold-sensitive and forms filaments at 15C (Xia, 2001). CspE is a cold shock protein homolog, but is constitutively expressed at 37C. CspE has transcription antitermination activity. CspE affects rpoS and uspA expression. CspE is a negative regulator of cspA transcription. CspE binds ssDNA containing six or more contiguous dT residues with high affinity (Johnston, 2006).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.