hupA:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''hupA''  
''hupA''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3992, b4000, JW3964, G119, hydL''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''ECK3992, b4000, JW3964, G119, hydL''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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DNA-binding protein HU-&alpha; (HU-2)<ref name='LIB:EcoCyc10.6'/>; Transcriptional dual regulator  HU-&alpha; (HU-2)<ref name='LIB:EcoCyc11.1'/>;  
DNA-binding protein HU-&alpha; (HU-2)<ref name='LIB:EcoCyc10.6'/>; Transcriptional dual regulator  HU-&alpha; (HU-2)<ref name='LIB:EcoCyc11.1'/>;  
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Histone-like protein HU-alpha, HU-2<ref name='LIB:EcoGene'/>
Histone-like protein HU-alpha, HU-2<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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HU, DNA-binding transcriptional regulator, alpha subunit<ref name='LIB:Riley_2006'/>, B4000<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HydL<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HupA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
HU, DNA-binding transcriptional regulator, alpha subunit<ref name='LIB:Riley_2006'/>, B4000<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HydL<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HupA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Molecular Function'''
* GO:0016564 transcription repressor activity ([http://www.geneontology.org/GO.evidence.shtml IEP,IDA])
* GO:0016563 transcription activator activity ([http://www.geneontology.org/GO.evidence.shtml IDA,IEP])
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI])
'''Biological Process'''
* GO:0006350 transcription ([http://www.geneontology.org/GO.evidence.shtml IDA,IEP])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:hupA|hupA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:hupA|hupA]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=hupA&loc=MG1655:4198304..4198576,W3110:3436400..3436128,DH10B:4298000..4298272,REL606:4179893..4180165 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4179893&end=4180165&gene=hupA&aa=mnktqlidviaekaelsktqakaalestlaaiteslkegdavqlvgfgtfkvnhraertgrnpqtgkeikiaaanvpafvsgkalkdavk Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hupA+AND+escherichia+coli Pubmed(hupA)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=hupA Textpresso(hupA)]


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Revision as of 23:51, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

hupA

Gene Synonym(s)

ECK3992, b4000, JW3964, G119, hydL[1][2]

Product Desc.

DNA-binding protein HU-α (HU-2)[2]; Transcriptional dual regulator HU-α (HU-2)[3];

Component of HU Transcriptional dual regulator[3]

Histone-like protein HU-alpha, HU-2[4]

Product Synonyms(s)

HU, DNA-binding transcriptional regulator, alpha subunit[1], B4000[2][1], HydL[2][1], HupA[2][1]

Function from GO

Molecular Function

Biological Process

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hupA[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(hupA)    Textpresso(hupA)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


HU concentration in the cell determines the mechanical effect; flexible bends responsible for compaction occur at concentrations <100nM, while increased concentrations result in the formation of a rigid nucleoprotein filament and no significant concentration. Mutant HU alters structure and function of the chromosome. HT_Cmplx32_Mem: CspC+Hns+HupA.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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