iscS:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''iscS''  
''iscS''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK2527, b2530, JW2514, csdB, yfhO, nifS, yzzO, nuvC?''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''ECK2527, b2530, JW2514, csdB, yfhO, nifS, yzzO, nuvC?''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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cysteine desulfurase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
cysteine desulfurase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Cysteine desulfurase used in synthesis of Fe-S cluster; tRNA 4-thiouridine sulfurtransferase; transfers sulfur to binding partner SirA(TusA) to form C19 persulfide used to thiolate tRNA U34<ref name='LIB:EcoGene'/>
Cysteine desulfurase used in synthesis of Fe-S cluster; tRNA 4-thiouridine sulfurtransferase; transfers sulfur to binding partner SirA(TusA) to form C19 persulfide used to thiolate tRNA U34<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent<ref name='LIB:Riley_2006'/>, YzzO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YfhO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IscS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B2530<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent<ref name='LIB:Riley_2006'/>, YzzO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YfhO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IscS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B2530<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Molecular Function'''
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI])
* GO:0009000 selenocysteine lyase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0031071 cysteine desulfurase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Biological Process'''
* GO:0016226 iron-sulfur cluster assembly ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0018131 oxazole or thiazole biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0031119 tRNA pseudouridine synthesis ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:iscRSUA|iscRSUA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:iscRSUA|iscRSUA]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=iscS&loc=MG1655:2659553..2658339,W3110:2660187..2658973,REL606:2582230..2581016,DH10B:2751318..2750104 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2751318&end=2750104&gene=iscS&aa=mklpiyldysattpvdprvaekmmqfmtmdgtfgnpasrshrfgwqaeeavdiarnqiadlvgadpreivftsgatesdnlaikgaanfyqkkgkhiitsktehkavldtcrqleregfevtylapqrngiidlkeleaamrddtilvsimhvnneigvvqdiaaigemcrargiiyhvdatqsvgklpidlsqlkvdlmsfsghkiygpkgigalyvrrkprvrieaqmhggghergmrsgtlpvhqivgmgeayriakeematemerlrglrnrlwngikdieevylngdlehgapnilnvsfnyvegeslimalkdlavssgsactsaslepsyvlralglndelahssirfslgrftteeeidytielvrksigrlrdlsplwemykqgvdlnsiewahh Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=iscS+AND+escherichia+coli Pubmed(iscS)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=iscS Textpresso(iscS)]


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Revision as of 23:48, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

iscS

Gene Synonym(s)

ECK2527, b2530, JW2514, csdB, yfhO, nifS, yzzO, nuvC?[1][2]

Product Desc.

cysteine desulfurase[2][3];

Component of cysteine desulfurase[3]

Cysteine desulfurase used in synthesis of Fe-S cluster; tRNA 4-thiouridine sulfurtransferase; transfers sulfur to binding partner SirA(TusA) to form C19 persulfide used to thiolate tRNA U34[4]

Product Synonyms(s)

cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent[1], YzzO[2][1], YfhO[2][1], IscS[2][1], B2530[2][1]

Function from GO

Molecular Function

Biological Process

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): iscRSUA[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(iscS)    Textpresso(iscS)

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See Help:Quickview for help with entering information in the Quickview table.

Notes

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IscS has selenocysteine lyase activity in vitro.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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