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References Suggestions


Standard Name


Gene Synonym(s)

ECK2527, b2530, JW2514, csdB, yfhO, nifS, yzzO, nuvC?[1][2], nuvC

Product Desc.

cysteine desulfurase[2][3];

Component of cysteine desulfurase[3]

Cysteine desulfurase used in synthesis of Fe-S cluster; tRNA 4-thiouridine sulfurtransferase; transfers sulfur to binding partner SirA(TusA) to form C19 persulfide used to thiolate tRNA U34[4]

Product Synonyms(s)

cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent[1], YzzO[2][1], YfhO[2][1], IscS[2][1], B2530[2][1] , ECK2527, JW2514, nuvC, yfhO, yzzO, b2530

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): iscRSUA[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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IscS has selenocysteine lyase activity in vitro.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.