yjgF:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''yjgF''  
''yjgF''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK4238, b4243, JW5755''<ref name='LIB:Riley_2006'/>
''ECK4238, b4243, JW5755''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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conserved protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
conserved protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Function unknown; Salmonella ortholog required for full IlvE activity and for the dependence of the alternative pyrimidine biosynthesis (APB) pathway of thiamine biosynthesis upon the oxidative pentose phosphate pathway; serine sensitivity; trimeric<ref name='LIB:EcoGene'/>
Function unknown; Salmonella ortholog required for full IlvE activity and for the dependence of the alternative pyrimidine biosynthesis (APB) pathway of thiamine biosynthesis upon the oxidative pentose phosphate pathway; serine sensitivity; trimeric<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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ketoacid-binding protein product<ref name='LIB:Riley_2006'/>, B4243 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjgF product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
ketoacid-binding protein product<ref name='LIB:Riley_2006'/>, B4243 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjgF product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Cellular Component'''
* GO:0005624 membrane fraction ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0005739 mitochondrion ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:yjgF|yjgF]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:yjgF|yjgF]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=yjgF&loc=MG1655:4468936..4468550,W3110:4475593..4475207,REL606:4454190..4453804,DH10B:4570744..4570358 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4570744&end=4570358&gene=yjgF&aa=msqtfyrcnkgeimsktiatenapaaigpyvqgvdlgnmiitsgqipvnpktgevpadvaaqarqsldnvkaiveaaglkvgdivkttvfvkdlndfatvnatyeafftehnatfparscvevarlpkdvkieieaiavrr Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=yjgF+AND+escherichia+coli Pubmed(yjgF)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=yjgF Textpresso(yjgF)]


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Revision as of 22:55, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

yjgF

Gene Synonym(s)

ECK4238, b4243, JW5755[1]

Product Desc.

conserved protein[2][3];

Component of YjgF homotrimer[3]

Function unknown; Salmonella ortholog required for full IlvE activity and for the dependence of the alternative pyrimidine biosynthesis (APB) pathway of thiamine biosynthesis upon the oxidative pentose phosphate pathway; serine sensitivity; trimeric[4]

Product Synonyms(s)

ketoacid-binding protein product[1], B4243 product[2][1], YjgF product[2][1]

Function from GO

Cellular Component

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yjgF[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(yjgF)    Textpresso(yjgF)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


YjgF, RutC, TdcF, YoaB and YjgH are paralogs and members of a highly conserved YjgF family (pfam:PF01042) with diverse mutant phenotypes and unknown molecular function; the family members form homotrimers, some binding 2-ketoglutarate or related compounds. The rat homolog PSP (perchloric acid-soluble protein) has been reported to have endoribonuclease activity, Endoribonuclease L, against ss mRNA, inhibiting translation, but this activity has not been demonstrated for other members.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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