yjgF:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
ridA |
|---|---|
| Gene Synonym(s) |
ECK4238, b4243, JW5755[1], JW5755, yjgF |
| Product Desc. |
Component of YjgF homotrimer[3] Function unknown; Salmonella ortholog required for full IlvE activity and for the dependence of the alternative pyrimidine biosynthesis (APB) pathway of thiamine biosynthesis upon the oxidative pentose phosphate pathway; serine sensitivity; trimeric[4] |
| Product Synonyms(s) |
ketoacid-binding protein[1], B4243[2][1], YjgF[2][1] , ECK4238, JW5755, b4243 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
YjgF, RutC, TdcF, YoaB and YjgH are paralogs and members of a highly conserved YjgF family (pfam:PF01042) with diverse mutant phenotypes and unknown molecular function; the family members form homotrimers, some binding 2-ketoglutarate or related compounds. The rat homolog PSP (perchloric acid-soluble protein) has been reported to have endoribonuclease activity, Endoribonuclease L, against ss mRNA, inhibiting translation, but this activity has not been demonstrated for other members.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
