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!align=left {{table heading style}} |Standard name
!align=left |Standard name
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UhpA  
UhpA  
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!align=left {{table heading style}} |Synonyms
!align=left |Synonyms
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B3669<ref name='LIB:EcoCyc10.6'/>, response regulator, positive activator of uhpT transcription (sensor, uhpB)<ref name='LIB:EcoCyc10.6'/>, transcriptional regulatory protein UhpA<ref name='LIB:EcoCyc10.6'/>, unphosphorylated transcriptional regulatory protein UhpA<ref name='LIB:EcoCyc10.6'/>, unmodified transcriptional regulatory protein UhpA<ref name='LIB:EcoCyc10.6'/>  
B3669<ref name='LIB:EcoCyc10.6'/>, response regulator, positive activator of uhpT transcription (sensor, uhpB)<ref name='LIB:EcoCyc10.6'/>, transcriptional regulatory protein UhpA<ref name='LIB:EcoCyc10.6'/>, unphosphorylated transcriptional regulatory protein UhpA<ref name='LIB:EcoCyc10.6'/>, unmodified transcriptional regulatory protein UhpA<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table heading style}} |Product description
!align=left |Product description
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UhpA transcriptional activator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
UhpA transcriptional activator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Response regulator of two component system required for uhpT transcription<ref name='LIB:EcoGene'/>
Response regulator of two component system required for uhpT transcription<ref name='LIB:EcoGene'/>
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!align=left {{table heading style}} |EC number (for enzymes)
!align=left |EC number (for enzymes)
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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Experiment(s):EBI-1146459<br />  
Experiment(s):EBI-1146459<br />  


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!align=left {{table heading style}} |Sequence
!align=left |Sequence
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[http://biocyc.org/ECOLI/sequence-aa?object=PHOSPHO-UHPA at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=PHOSPHO-UHPA at EcoCyc]  
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GVSNDVELAR RMFDGW</pre>  
GVSNDVELAR RMFDGW</pre>  
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!align=left {{table heading style}} |Length
!align=left |Length
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196
196
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!align=left {{table heading style}} |Mol. Wt
!align=left |Mol. Wt
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20.889 kDa
20.889 kDa
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!align=left {{table heading style}} |pI
!align=left |pI
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6.0 (calculated)
6.0 (calculated)
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!align=left {{table heading style}} |Extinction coefficient
!align=left |Extinction coefficient
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6,990 - 7,490 (calc based on 1 Y, 1 W, and 4 C residues)
6,990 - 7,490 (calc based on 1 Y, 1 W, and 4 C residues)


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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left {{table heading style}} |Models
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View models at:
View models at:
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* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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Revision as of 01:06, 10 January 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

UhpA

Synonyms

B3669[1], response regulator, positive activator of uhpT transcription (sensor, uhpB)[1], transcriptional regulatory protein UhpA[1], unphosphorylated transcriptional regulatory protein UhpA[1], unmodified transcriptional regulatory protein UhpA[1]

Product description

UhpA transcriptional activator[1][2]

Response regulator of two component system required for uhpT transcription[3]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0043565

sequence-specific DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000792

F

Seeded from EcoCyc [4]

complete

GO:0008643

carbohydrate transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0762

P

Seeded from EcoCyc [4]

complete

GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc [4]

complete

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR000792
InterPro:IPR001789
SP_KW:KW-0805

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0006350

transcription

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc [4]

complete

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0005622

intracellular

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000792

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0005351

sugar:hydrogen symporter activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0762

F

Seeded from EcoCyc [4]

complete

GO:0003700

transcription factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000792

F

Seeded from EcoCyc [4]

complete

GO:0003677

DNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0000160

two-component signal transduction system (phosphorelay)

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR001789
SP_KW:KW-902

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0000156

two-component response regulator activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001789

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[6]

IPI: Inferred from Physical Interaction

UniProtKB:P0ADC1

F

Seeded from EcoCyc [4]

complete

GO:0016563

transcription activator activity

F

Seeded from EcoCyc 11.1[2].

required fields missing

GO:0016052

carbohydrate catabolic process

P

Seeded from EcoCyc 11.1[2].

required fields missing

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rlpB

PMID:16606699[6]

Experiment(s):EBI-1146459
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Notes

Downregulates glucose-6-phosphate and fructose-6-phosphate respiration in E. coli. Zhou (2003)

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes

cytoplasm

From EcoCyc[2]


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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MITVALIDDH LIVRSGFAQL LGLEPDLQVV AEFGSGREAL AGLPGRGVQV CICDISMPDI
SGLELLSQLP KGMATIMLSV HDSPALVEQA LNAGARGFLS KRCSPDELIA AVHTVATGGC
YLTPDIAIKL ASGRQDPLTK RERQVAEKLA QGMAVKEIAA ELGLSPKTVH VHRANLMEKL
GVSNDVELAR RMFDGW
Length

196

Mol. Wt

20.889 kDa

pI

6.0 (calculated)

Extinction coefficient

6,990 - 7,490 (calc based on 1 Y, 1 W, and 4 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=uhpA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:UHPA-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0AGA6

PFAM (EcoliWiki Page)

PFAM:PF00072

RefSeq (EcoliWiki Page)

RefSeq:NP_418125


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. ↑ 6.0 6.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

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