relA:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''relA''  
''relA''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK2778, b2784, JW2755, RC''<ref name='LIB:Riley_2006'/>
''ECK2778, b2784, JW2755, RC''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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RELA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
RELA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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ATP:GTP 3'-pyrophosphotransferase, ppGpp synthetase I; required for ppGpp synthesis during stringent response to amino acid starvation; self regulated<ref name='LIB:EcoGene'/>
ATP:GTP 3'-pyrophosphotransferase, ppGpp synthetase I; required for ppGpp synthesis during stringent response to amino acid starvation; self regulated<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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(p)ppGpp synthetase I/GTP pyrophosphokinase<ref name='LIB:Riley_2006'/>, B2784<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RelA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ppGpp synthase I<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
(p)ppGpp synthetase I/GTP pyrophosphokinase<ref name='LIB:Riley_2006'/>, B2784<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RelA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ppGpp synthase I<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:relA-mazEF|relA-mazEF]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>, relA-chpRA, chpA  
transcription unit(s): [[:Category:Txn_unit:relA-mazEF|relA-mazEF]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>, relA-chpRA, chpA  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 05:33, 9 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

relA

Gene Synonym(s)

ECK2778, b2784, JW2755, RC[1]

Product Desc.

RELA[2][3]

ATP:GTP 3'-pyrophosphotransferase, ppGpp synthetase I; required for ppGpp synthesis during stringent response to amino acid starvation; self regulated[4]

Product Synonyms(s)

(p)ppGpp synthetase I/GTP pyrophosphokinase[1], B2784[2][1], RelA[2][1], ppGpp synthase I[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): relA-mazEF[2][3], relA-chpRA, chpA

Regulation/Activity


See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


RelA has two physically and functionally distinct domains, the N-terminal domain, amino acids 1 to 455, is responsible for (p)ppGpp synthesis, and the C-terminal domain, amino acids 456 to 744, is responsible for self regulation.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.