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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''parC''  
''parC''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3010, b3019, JW2987''<ref name='LIB:Riley_2006'/>
''ECK3010, b3019, JW2987''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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topoisomerase IV subunit A<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
topoisomerase IV subunit A<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Topoisomerase IV, subunit A, ATP-dependent, type II; chromosome decatenase; relaxes both positive and negative supercoils; DNA unknotting activity; heterotetrameric<ref name='LIB:EcoGene'/>
Topoisomerase IV, subunit A, ATP-dependent, type II; chromosome decatenase; relaxes both positive and negative supercoils; DNA unknotting activity; heterotetrameric<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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DNA topoisomerase IV, subunit A<ref name='LIB:Riley_2006'/>, B3019<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ParC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
DNA topoisomerase IV, subunit A<ref name='LIB:Riley_2006'/>, B3019<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ParC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0007059 chromosome segregation ([http://www.geneontology.org/GO.evidence.shtml IMP,IDA])
* GO:0006261 DNA-dependent DNA replication ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0006265 DNA topological change ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0030541 plasmid partitioning ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0007062 sister chromatid cohesion ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Cellular Component'''
* GO:0005737 cytoplasm ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0019897 extrinsic to plasma membrane ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing) ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Molecular Function'''
* GO:0003918 DNA topoisomerase (ATP-hydrolyzing) activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0003916 DNA topoisomerase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0003677 DNA binding ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:parC|parC]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:parC|parC]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=parC&loc=MG1655:3163995..3161737,W3110:3164629..3162371,REL606:3100145..3097887,DH10B:3261740..3259482 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3261740&end=3259482&gene=parC&aa=msdmaerlalheftenaylnysmyvimdralpfigdglkpvqrrivyamselglnasakfkksartvgdvlgkyhphgdsacyeamvlmaqpfsyryplvdgqgnwgapddpksfaamrytesrlskyselllselgqgtadwvpnfdgtlqepkmlparlpnillngttgiavgmatdipphnlrevaqaaialidqpkttldqlldivqgpdypteaeiitsraeirkiyengrgsvrmravwkkedgavvisalphqvsgarvleqiaaqmrnkklpmvddlrdesdhenptrlvivprsnrvdmdqvmnhlfattdleksyrinlnmigldgrpavknlleilsewlvfrrdtvrrrlnyrlekvlkrlhilegllvaflnidevieiirnedepkpalmsrfgltetqaeailelklrhlakleemkirgeqselekerdqlqgilaserkmnnllkkelqadaqaygddrrsplqereeakamsehdmlpsepvtivlsqmgwvrsakghdidapglnykagdsfkaavkgksnqpvvfvdstgrsyaidpitlpsargqgepltgkltlppgatvdhmlmesddqkllmasdagygfvctfndlvarnragkalitlpenahvmppvviedasdmllaitqagrmlmfpvsdlpqlskgkgnkiinipsaeaargedglaqlyvlppqstltihvgkrkiklrpeelqkvtgergrrgtlmrglqridrveidsprrassgdsee Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=parC+AND+escherichia+coli Pubmed(parC)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=parC Textpresso(parC)]


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Revision as of 23:37, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

parC

Gene Synonym(s)

ECK3010, b3019, JW2987[1]

Product Desc.

topoisomerase IV subunit A[2][3];

Component of dimer of topoisomerase IV subunit A[3]; topoisomerase IV[3]

Topoisomerase IV, subunit A, ATP-dependent, type II; chromosome decatenase; relaxes both positive and negative supercoils; DNA unknotting activity; heterotetrameric[4]

Product Synonyms(s)

DNA topoisomerase IV, subunit A[1], B3019[2][1], ParC[2][1]

Function from GO

Biological Process

Cellular Component

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): parC[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(parC)    Textpresso(parC)

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Notes

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ParC physically interacts with SeqA. Topo IV is stimulated by SeqA.[4]



References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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