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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''hisF''  
''hisF''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK2020, b2025, JW2007''<ref name='LIB:Riley_2006'/>
''ECK2020, b2025, JW2007''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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imidazole glycerol phosphate synthase, HisF subunit<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
imidazole glycerol phosphate synthase, HisF subunit<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Cyclase component of imidazole glycerol phosphate (IGP) synthase<ref name='LIB:EcoGene'/>
Cyclase component of imidazole glycerol phosphate (IGP) synthase<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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imidazole glycerol phosphate synthase, catalytic subunit with HisH<ref name='LIB:Riley_2006'/>, B2025<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HisF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, hisF enzyme<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
imidazole glycerol phosphate synthase, catalytic subunit with HisH<ref name='LIB:Riley_2006'/>, B2025<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HisF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, hisF enzyme<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Cellular Component'''
* GO:0009382 imidazoleglycerol-phosphate synthase complex ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Molecular Function'''
* GO:0000107 imidazoleglycerol-phosphate synthase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Biological Process'''
* GO:0000105 histidine biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:hisBHAFI|hisBHAFI]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:hisLGDCBHAFI|hisLGDCBHAFI]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:hisBHAFI|hisBHAFI]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:hisLGDCBHAFI|hisLGDCBHAFI]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=hisF&loc=MG1655:2093868..2094644,W3110:2097981..2098757,REL606:2025846..2026622,DH10B:2184876..2185652 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2184876&end=2185652&gene=hisF&aa=mlakriipcldvrdgqvvkgvqfrnheiigdivplakryaeegadelvfyditassdgrvvdkswvsrvaevidipfcvaggiksledaakilsfgadkisinspaladptlitrladrfgvqcivvgidtwydaetgkyhvnqytgdesrtrvtqwetldwvqevqkrgageivlnmmnqdgvrngydleqlkkvrevchvpliasggagtmehfleafrdadvdgalaasvfhkqiinigelkaylatqgveiric Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hisF+AND+escherichia+coli Pubmed(hisF)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=hisF Textpresso(hisF)]


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Revision as of 23:52, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

hisF

Gene Synonym(s)

ECK2020, b2025, JW2007[1]

Product Desc.

imidazole glycerol phosphate synthase, HisF subunit[2][3];

Component of imidazole glycerol phosphate synthase[2][3]

Cyclase component of imidazole glycerol phosphate (IGP) synthase[4]

Product Synonyms(s)

imidazole glycerol phosphate synthase, catalytic subunit with HisH[1], B2025[2][1], HisF[2][1], hisF enzyme[2][1]

Function from GO

Cellular Component

Molecular Function

Biological Process

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hisBHAFI[2], hisLGDCBHAFI[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(hisF)    Textpresso(hisF)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


N-terminus of purified HisF was sequenced by Klem and Davisson (1993), and the fMet is not clipped. Omitted from Verified set because natural RBS was not used. Natural RBS is very good and this is almost certainly the in vivo start.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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