add:Quickview: Difference between revisions

From EcoliWiki
Jump to navigation Jump to search
← Older editNewer edit →
Update TableEdit tables.
update QV table
Line 27: Line 27:


|-
|-
!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
||
||
''add''  
''add''  
|-
|-
!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
||
||
''ECK1618, b1623, JW1615''<ref name='LIB:Riley_2006'/>
''ECK1618, b1623, JW1615''<ref name='LIB:Riley_2006'/>
|-
|-
!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
||
||


Adenosine deaminase; mutants affect growth on deoxyadenosine in purA, B mutants<ref name='LIB:EcoGene'/>
Adenosine deaminase; mutants affect growth on deoxyadenosine in purA, B mutants<ref name='LIB:EcoGene'/>
|-
|-
!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
||
||
adenosine deaminase<ref name='LIB:Riley_2006'/>, B1623<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Add<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
adenosine deaminase<ref name='LIB:Riley_2006'/>, B1623<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Add<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
|-
|-
!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
||
||
'''Molecular Function'''
* GO:0004000 adenosine deaminase activity ([http://www.geneontology.org/GO.evidence.shtml IDA,IMP])
* GO:0005488 binding ([http://www.geneontology.org/GO.evidence.shtml ISS])
'''Biological Process'''
* GO:0015950 purine nucleotide interconversion ([http://www.geneontology.org/GO.evidence.shtml IGI])
* GO:0009168 purine ribonucleoside monophosphate biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IGI])
* GO:0006154 adenosine catabolic process ([http://www.geneontology.org/GO.evidence.shtml IGI])
* GO:0032261 purine nucleotide salvage ([http://www.geneontology.org/GO.evidence.shtml IGI])
* GO:0043103 hypoxanthine salvage ([http://www.geneontology.org/GO.evidence.shtml IGI])
* GO:0046101 hypoxanthine biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IGI])
'''Cellular Component'''
* GO:0005737 cytoplasm ([http://www.geneontology.org/GO.evidence.shtml IC])


|-
|-
!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
||
 
|-
!align=left {{table_heading_style}} |Regulation/Expression
||
||
transcription unit(s): [[:Category:Txn_unit:add|add]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:add|add]]<ref name='LIB:EcoCyc10.6'/>  
|-
|-
!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
||
||


|-
!align=left {{table_heading_style}} |Quick Links
||
[http://ecoliwiki.net/tools/display_dna.php?gene=add&loc=MG1655:1700257..1701258,W3110:1703947..1704948,DH10B:1791218..1792219,REL606:1679427..1680428 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1679427&end=1680428&gene=add&aa=midttlpltdihrhldgnirpqtilelgrqynislpaqsletliphvqvianepdlvsfltkldwgvkvlasldacrrvafeniedaarhglhyvelrfspgymamahqlpvagvveavidgvregcrtfgvqakligimsrtfgeaacqqeleaflahrdqitaldlagdelgfpgslflshfnrardagwhitvhageaagpesiwqairelgaerighgvkaiedralmdflaeqqigiescltsniqtstvaelaahplktflehgirasintddpgvqgvdiiheytvaapaaglsreqirqaqinglemaflsaeekralrekvaak Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=add+AND+escherichia+coli Pubmed(add)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=add Textpresso(add)]


|- class="tableEdit_footer"  
|- class="tableEdit_footer"  

Revision as of 00:13, 22 January 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

add

Gene Synonym(s)

ECK1618, b1623, JW1615[1]

Product Desc.

Adenosine deaminase; mutants affect growth on deoxyadenosine in purA, B mutants[2]

Product Synonyms(s)

adenosine deaminase[1], B1623[3][1], Add[3][1]

Function from GO

Molecular Function

Biological Process

Cellular Component

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): add[3]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(add)    Textpresso(add)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Adenosine deaminase is an enzyme involved in purine metabolism, which irreversibly deaminates both adenosine and deoxyadenosine to inosine and deoxyinosine. The optimal pH for this enzyme is around 7.5-8, but activity is irreversibly lost when pH is lower than 2.7 or higher than 9.5. Adenosine deaminase is sensitive to heavy metals, such as Ag+, Cu2+, and Cr3+, and reacts with them irreversibly (Koch, 1958). [4]

Complications in purine metabolism often result in various disorders in humans. Deficiencies amounts of adenosine deaminase result in diseases such as severe combined immunodeficiency disorder (SCID) and lymphopenia.

Binds TrxA (Kumar, 2004).[2]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ KOCH, AL & VALLEE, G (1959) The properties of adenosine deaminase and adenosine nucleoside phosphorylase in extracts of Escherichia coli. J. Biol. Chem. 234 1213-8 PubMed


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=add:Quickview&oldid=1032505"