metA:Gene Product(s): Difference between revisions

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|-
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!align=left {{table heading style}} |Standard name
!align=left |Standard name
||
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MetA  
MetA  
|-
|-
!align=left {{table heading style}} |Synonyms
!align=left |Synonyms
||
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homoserine transsuccinylase<ref name='LIB:Riley_2006'/>, B4013<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MetA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
homoserine transsuccinylase<ref name='LIB:Riley_2006'/>, B4013<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MetA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
|-
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!align=left {{table heading style}} |Product description
!align=left |Product description
||
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MetA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
MetA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Homoserine O-transsuccinylase; also called homoserine O-succinyltransferase<ref name='LIB:EcoGene'/>
Homoserine O-transsuccinylase; also called homoserine O-succinyltransferase<ref name='LIB:EcoGene'/>
|-
|-
!align=left {{table heading style}} |EC number (for enzymes)
!align=left |EC number (for enzymes)
||
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.46 2.3.1.46]<ref name='LIB:Riley_2006'/>
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.46 2.3.1.46]<ref name='LIB:Riley_2006'/>


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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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complete  
complete  


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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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Experiment(s):EBI-1147283<br />  
Experiment(s):EBI-1147283<br />  


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!|Compartment!!Description!!Evidence!!Source!!Notes
!|Compartment!!Description!!Evidence!!Source!!Notes


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|-
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!align=left {{table heading style}} |Sequence
!align=left |Sequence
||
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[http://biocyc.org/ECOLI/sequence-aa?object=HOMSUCTRAN-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=HOMSUCTRAN-MONOMER at EcoCyc]  
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LRHMNPTLD</pre>  
LRHMNPTLD</pre>  
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!align=left {{table heading style}} |Length
!align=left |Length
||
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309
309
|-
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!align=left {{table heading style}} |Mol. Wt
!align=left |Mol. Wt
||
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35.727 kDa
35.727 kDa
|-
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!align=left {{table heading style}} |pI
!align=left |pI
||
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5.0 (calculated)
5.0 (calculated)
|-
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!align=left {{table heading style}} |Extinction coefficient
!align=left |Extinction coefficient
||
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48,360 - 48,610 (calc based on 14 Y, 5 W, and 2 C residues)
48,360 - 48,610 (calc based on 14 Y, 5 W, and 2 C residues)


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[http://www.uniprot.org/uniprot/P07623#section_features UniProt:P07623]  
[http://www.uniprot.org/uniprot/P07623#section_features UniProt:P07623]  


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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left {{table heading style}} |Models
!align=left |Models
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View models at:
View models at:
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* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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Revision as of 02:08, 9 January 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MetA

Synonyms

homoserine transsuccinylase[1], B4013[2][1], MetA[2][1]

Product description

MetA[2][3];

Component of homoserine O-succinyltransferase[2][3]

Homoserine O-transsuccinylase; also called homoserine O-succinyltransferase[4]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

PMID:16606699[5]

IPI: Inferred from Physical Interaction

UniProtKB:P0A6F5

F

Seeded from EcoCyc [6]

complete

GO:0003824

catalytic activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0021

F

Seeded from EcoCyc [6]

complete

GO:0005737

cytoplasm

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR005697
SP_KW:KW-0963

C

Seeded from EcoCyc 12.5 [7]

complete

GO:0008415

acyltransferase activity

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR005697
SP_KW:KW-0012

F

Seeded from EcoCyc [6]

complete

GO:0008652

amino acid biosynthetic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0028

P

Seeded from EcoCyc [6]

complete

GO:0008899

homoserine O-succinyltransferase activity

GO_REF:0000003
GO_REF:0000020

IEA: Inferred from Electronic Annotation

EC:2.3.1.46
HAMAP:MF_00295

F

Seeded from EcoCyc 12.5 [7]

complete

GO:0009086

methionine biosynthetic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0486

P

Seeded from EcoCyc [6]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc [6]

complete

GO:0019281

methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine

GO_REF:0000002
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR005697
HAMAP:MF_00295

P

Seeded from EcoCyc 12.5 [7]

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of homoserine O-succinyltransferase

could be indirect

Protein

groL

PMID:16606699[5]

Experiment(s):EBI-1147283
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MPIRVPDELP AVNFLREENV FVMTTSRASG QEIRPLKVLI LNLMPKKIET ENQFLRLLSN
SPLQVDIQLL RIDSRESRNT PAEHLNNFYC NFEDIQDQNF DGLIVTGAPL GLVEFNDVAY
WPQIKQVLEW SKDHVTSTLF VCWAVQAALN ILYGIPKQTR TEKLSGVYEH HILHPHALLT
RGFDDSFLAP HSRYADFPAA LIRDYTDLEI LAETEEGDAY LFASKDKRIA FVTGHPEYDA
QTLAQEFFRD VEAGLDPDVP YNYFPHNDPQ NTPRASWRSH GNLLFTNWLN YYVYQITPYD
LRHMNPTLD
Length

309

Mol. Wt

35.727 kDa

pI

5.0 (calculated)

Extinction coefficient

48,360 - 48,610 (calc based on 14 Y, 5 W, and 2 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes

Initiator Methionine

1

Removed

UniProt:P07623

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=metA taxon=562,83333 </beststructure>

Models

View models at:

edit table

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:HOMSUCTRAN-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:P07623

UniProt (EcoliWiki Page)

UniProt:P07623

PFAM (EcoliWiki Page)

PFAM:PF04204

RefSeq (EcoliWiki Page)

RefSeq:NP_418437


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  7. ↑ 7.0 7.1 7.2 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7

Categories

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