eptA:Gene Product(s): Difference between revisions

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<span id="Structure"></span><big>'''Structure'''</big>
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<span id='Structure'></span><big>'''Structure'''</big><br />
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==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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===Notes===
===Notes===


Revision as of 15:43, 23 July 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

EptA product

Synonyms

predicted metal dependent hydrolase product[1], B4114 product[2][1], YjdB product[2][1], EptA product[2][1]

Product description

predicted metal-dependent hydrolase[2][3]

Lipid A phosphoethanolamine transferase, associated with polymyxin resistance[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0016021

integral to membrane

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR012549
SP_KW:KW-0812

C

Seeded from EcoCyc [5]

complete

GO:0016020

membrane

GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [6]

complete

GO:0008484

sulfuric ester hydrolase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000917

F

Seeded from EcoCyc [5]

complete

GO:0008152

metabolic process

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000917
InterPro:IPR001952

P

Seeded from EcoCyc 12.5 [6]

complete

GO:0003824

catalytic activity

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017849
InterPro:IPR017850

F

Seeded from EcoCyc [5]

complete

GO:0005886

plasma membrane

GO_REF:0000004
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997
SP_KW:KW-1003
SP_SL:SL-0037

C

Seeded from EcoCyc [5]

complete

GO:0003824

catalytic activity

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017849
InterPro:IPR017850

F

Seeded from EcoCyc

complete

GO:0005886

plasma membrane

GO_REF:0000004
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997
SP_KW:KW-1003
SP_SL:SL-0037

C

Seeded from EcoCyc

complete

GO:0008152

metabolic process

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000917
InterPro:IPR017849
InterPro:IPR017850

P

Seeded from EcoCyc

complete

GO:0008484

sulfuric ester hydrolase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000917

F

Seeded from EcoCyc

complete

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc

complete

GO:0016021

integral to membrane

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR012549
SP_KW:KW-0812

C

Seeded from EcoCyc

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Notes

plasma membrane


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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MRTLFDGNTV MLKRLLKRPS LNLLAWLLLA AFYISICLNI AFFKQVLQAL PLDSLHNVLV
FLSMPVVAFS VINIVLTLSS FLWLNRPLAC LFILVGAAAQ YFIMTYGIVI DRSMIANIID
TTPAESYALM TPQMLLTLGF SGVLAALIAC WIKIKPATSR LRSVLFRGAN ILVSVLLILL
VAALFYKDYA SLFRNNKELV KSLSPSNSIV ASWSWYSHQR LANLPLVRIG EDAHRNPLMQ
NEKRKNLTIL IVGETSRAEN FSLNGYPRET NPRLAKDNVV YFPNTASCGT ATAVSVPCMF
SDMPREHYKE ELAQHQEGVL DIIQRAGINV LWNDNDGGCK GACDRVPHQN VTALNLPDQC
INGECYDEVL FHGLEEYINN LQGDGVIVLH TIGSHGPTYY NRYPPQFRKF TPTCDTNEIQ
TCTKEQLVNT YDNTLVYVDY IVDKAINLLK EHQDKFTTSL VYLSDHGESL GENGIYLHGL
PYAIAPDSQK QVPMLLWLSE DYQKRYQVDQ NCLQKQAQTQ HYSQDNLFST LLGLTGVETK
YYQAADDILQ TCRRVSE
Length

557

Mol. Wt

62.803 kDa

pI

6.8 (calculated)

Extinction coefficient

77,240 - 78,865 (calc based on 26 Y, 7 W, and 13 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes

Domain

21 - 43

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

58 - 83

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

88 - 110

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

164 - 186

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

130 - 152

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

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<motif_map/>

tmhmm.php?gene=eptA&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure>eptA 562</beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11613-MONOMER

UniProt (EcoliWiki Page)

UniProt:P30845

PFAM (EcoliWiki Page)

PFAM:PF00884

RefSeq (EcoliWiki Page)

RefSeq:NP_418538

ModBase (EcoliWiki Page)

ModBase:P30845


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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ 6.0 6.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ 7.0 7.1 7.2 7.3 7.4 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed

Categories

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