nrdE:Gene Product(s): Difference between revisions
Data loaded by TableEdit_Loader. |
Data loaded by TableEdit_Loader. |
||
| Line 387: | Line 387: | ||
| | | | ||
GO: | GO:0006260 | ||
| | | | ||
DNA replication | |||
| | | | ||
GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br /> | GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
InterPro:IPR000788<br />InterPro:IPR008926<br />InterPro: | InterPro:IPR000788<br />InterPro:IPR008926<br />InterPro:IPR013509<br />InterPro:IPR013554<br />SP_KW:KW-0235 | ||
| | | | ||
P | |||
| | | | ||
Seeded from EcoCyc | Seeded from EcoCyc | ||
| Line 520: | Line 520: | ||
| | | | ||
GO: | GO:0009263 | ||
| | | | ||
deoxyribonucleotide biosynthetic process | |||
| | | | ||
PMID:7809142 | |||
| | | | ||
IGI: Inferred from Genetic Interaction | |||
| | | | ||
EcoliWiki:nrdA|EcoliWiki:nrdB | |||
| | | | ||
P | P | ||
Revision as of 03:28, 22 May 2009
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
NrdE |
|---|---|
| Synonyms |
ribonucleoside-diphosphate reductase 2, alpha subunit[1], B2675[2][1], NrdE[2][1] |
| Product description |
Component of ribonucleoside-diphosphate reductase 2, α subunit dimer[2][3]; ribonucleoside-diphosphate reductase 2[2][3] |
| EC number (for enzymes) | |
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0009263 |
deoxyribonucleotide biosynthetic process |
IGI: Inferred from Genetic Interaction |
EcoliWiki:nrdA|EcoliWiki:nrdB |
P |
Seeded from EcoCyc [5] |
complete | ||
| GO:0000166 |
nucleotide binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [5] |
complete | |||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [5] |
complete | |||
| GO:0004748 |
ribonucleoside-diphosphate reductase activity |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000788 |
F |
Seeded from EcoCyc 12.5 [6] |
complete | ||
| GO:0005515 |
protein binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [5] |
complete | |||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [6] |
complete | |||
| GO:0005971 |
ribonucleoside-diphosphate reductase complex |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000788 |
C |
Seeded from EcoCyc 12.5 [6] |
complete | ||
| GO:0006260 |
DNA replication |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000788 |
P |
Seeded from EcoCyc 12.5 [6] |
complete | ||
| GO:0016491 |
oxidoreductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [5] |
complete | |||
| GO:0005737 |
cytoplasm |
ISA: Inferred from Sequence Alignment |
C |
complete | ||||
| GO:0055114 |
oxidation reduction |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [5] |
complete | |||
| GO:0000166 |
nucleotide binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc |
complete | |||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc |
complete | |||
| GO:0004748 |
ribonucleoside-diphosphate reductase activity |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000788 |
F |
Seeded from EcoCyc |
complete | |
| GO:0005515 |
protein binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc |
complete | |||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc |
complete | |||
| GO:0006260 |
DNA replication |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000788 |
P |
Seeded from EcoCyc |
complete | |
| GO:0015949 |
nucleobase, nucleoside and nucleotide interconversion |
IGI: Inferred from Genetic Interaction |
EcoliWiki:nrdA|EcoliWiki:nrdB |
P |
A plasmid expressing nrdEFHI genes from Salmonella was capable of complementing nrdAB- mutations in E. coli. |
complete | ||
| GO:0005524 |
ATP binding |
GO:0016959 |
ISA: Inferred from Sequence Alignment |
F |
complete | |||
|
Contributes to |
GO:0016959 |
class I ribonucleotide reductase activity |
IGI: Inferred from Genetic Interaction |
EcoliWiki:nrdA|EcoliWiki:nrdB |
F |
A plasmid expressing nrdEFHI genes from Salmonella was capable of complementing nrdAB- mutations in E. coli. |
complete | |
|
Contributes to |
GO:0004748 |
ribonucleoside-diphosphate reductase activity |
IGI: Inferred from Genetic Interaction |
EcoliWiki:nrdA|EcoliWiki:nrdB |
F |
complete | ||
| GO:0005971 |
ribonucleoside-diphosphate reductase complex |
IGI: Inferred from Genetic Interaction |
EcoliWiki:nrdA|EcoliWiki:nrdB |
C |
complete | |||
| GO:0009263 |
deoxyribonucleotide biosynthetic process |
IGI: Inferred from Genetic Interaction |
EcoliWiki:nrdA|EcoliWiki:nrdB |
P |
complete | |||
| GO:0009263 |
deoxyribonucleotide biosynthetic process |
IGI: Inferred from Genetic Interaction |
EcoliWiki:nrdA|EcoliWiki:nrdB |
P |
Seeded from EcoCyc |
complete | ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of ribonucleoside-diphosphate reductase 2, α subunit dimer |
could be indirect |
||
|
Protein |
intS |
Experiment(s):EBI-1143641 | ||
|
Protein |
tusE |
Experiment(s):EBI-1143641 | ||
|
Protein |
groL |
Experiment(s):EBI-1143641 | ||
|
Protein |
yagA |
Experiment(s):EBI-1143641 | ||
|
Protein |
ygeV |
Experiment(s):EBI-1143641 | ||
|
Protein |
ydcS |
Experiment(s):EBI-1143641 | ||
|
Protein |
ytfM |
Experiment(s):EBI-1143641 | ||
|
Protein |
rplB |
Experiment(s):EBI-1143641 | ||
|
Protein |
Subunits of ribonucleoside-diphosphate reductase 2 |
could be indirect |
| |
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
| edit table |
Notes
Structure and Physical Properties
Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MATTTAECLT QETMDYHALN AMLNLYDSAG RIQFDKDRQA VDAFIATHVR PNSVTFSSQQ QRLNWLVNEG YYDESVLNRY SRDFVITLFT HAHTSGFRFQ TFLGAWKFYT SYTLKTFDGK RYLEDFADRV TMVALTLAQG DETLALQLTD EMLSGRFQPA TPTFLNCGKQ QRGELVSCFL LRIEDNMESI GRAVNSALQL SKRGGGVAFL LSNLREAGAP IKRIENQSSG VIPVMKMLED AFSYANQLGA RQGAGAVYLH AHHPDILRFL DTKRENADEK IRIKTLSLGV VIPDITFHLA KENAQMALFS PYDVERVYGK PFADVAISQH YDELVADERI RKKYLNARDF FQRLAEIQFE SGYPYIMYED TVNRANPIAG RINMSNLCSE ILQVNSASEY DENLDYTRTG HDISCNLGSL NIAHTMDSPD FARTVETAVR GLTAVSDMSH IRSVPSIEAG NAASHAIGLG QMNLHGYLAR EGIAYGSPEA LDFTNLYFYA ITWHALRTSM LLARERGETF AGFKQSRYAS GEYFSQYLQG NWQPKTAKVG ELFTRSGITL PTREMWAQLR DDVMRYGIYN QNLQAVPPTG SISYINHATS SIHPIVAKVE IRKEGKTGRV YYPAPFMTNE NLALYQDAYE IGAEKIIDTY AEATRHVDQG LSLTLFFPDT ATTRDINKAQ IYAWRKGIKT LYYIRLRQMA LEGTEIEGCV SCAL |
|---|---|
| Length |
714 |
| Mol. Wt |
80.48 kDa (calc) [2] |
| pI | |
| Extinction coefficient |
88130 - 89005 (calc based on 37 Y, 6 W, and 7 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
| Structures |
<beststructure>nrdE 562</beststructure> |
|---|---|
| Models |
View models at: |
| edit table |
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 Jordan, A et al. (1994) A second class I ribonucleotide reductase in Enterobacteriaceae: characterization of the Salmonella typhimurium enzyme. Proc. Natl. Acad. Sci. U.S.A. 91 12892-6 PubMed
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
- ↑ 6.0 6.1 6.2 6.3 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
Categories
- GO:0009263 ! deoxyribonucleotide biosynthetic process
- GO:0000166 ! nucleotide binding
- GO:0003824 ! catalytic activity
- GO:0004748 ! ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
- GO:0005515 ! protein binding
- GO:0005524 ! ATP binding
- GO:0005971 ! ribonucleoside-diphosphate reductase complex
- GO:0006260 ! DNA replication
- GO:0016491 ! oxidoreductase activity
- GO:0005737 ! cytoplasm
- GO:0055114 ! oxidation-reduction process
- GO:0015949 ! nucleobase-containing small molecule interconversion
- GO:0016959 ! class I ribonucleotide reductase activity
- Proteins
- GO:0015949 ! nucleobase, nucleoside and nucleotide interconversion
- Complex:ribonucleoside-diphosphate reductase 2, α subunit dimer
- Complex:ribonucleoside-diphosphate reductase 2