bglF:Gene Product(s): Difference between revisions

Standard name	BglF
Synonyms	fused beta-glucoside-specific PTS enzymes: IIA component^[1], IIB component^[1], IIC component^[1], B3722^[2]^[1], BglS^[2]^[1], BglF^[2]^[1]
Product description	BglF^[2]^[3]; Component of EIIBgl^[2]^[3] PTS system EIIABC enzyme, beta-glucoside phosphotransferase; BglG kinase/dephosphorylase; membrane-bound protein; binds BglG^[4]
EC number (for enzymes)	2.7.1.69^[1]
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system	GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR001127 InterPro:IPR001996 InterPro:IPR003352 InterPro:IPR004719 InterPro:IPR011297 InterPro:IPR011535 SP_KW:KW-0598	P	Seeded from EcoCyc ^[5]	complete
	GO:0008643	carbohydrate transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0762	P	Seeded from EcoCyc ^[5]	complete
	GO:0008982	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000003	IEA: Inferred from Electronic Annotation	InterPro:IPR003352 InterPro:IPR004719 InterPro:IPR011297 InterPro:IPR011535 EC:2.7.1.69	F	Seeded from EcoCyc ^[5]	complete
	GO:0005351	sugar:hydrogen symporter activity	GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR001127 InterPro:IPR001996 InterPro:IPR003352 SP_KW:KW-0762	F	Seeded from EcoCyc ^[5]	complete
	GO:0006810	transport	GO_REF:0000002 GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR001127 InterPro:IPR001996 SP_KW:KW-0813	P	Seeded from EcoCyc ^[5]	complete
	GO:0016740	transferase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0808	F	Seeded from EcoCyc ^[5]	complete
	GO:0016020	membrane	GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000004 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR001127 InterPro:IPR001996 InterPro:IPR003352 SP_KW:KW-0397 SP_KW:KW-0472	C	Seeded from EcoCyc 12.5 ^[6]	complete
	GO:0016021	integral to membrane	GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR004719 SP_KW:KW-0812	C	Seeded from EcoCyc ^[5]	complete
	GO:0005886	plasma membrane	GO_REF:0000004 GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037	C	Seeded from EcoCyc ^[5]	complete
	GO:0016301	kinase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0418	F	Seeded from EcoCyc ^[5]	complete
	GO:0005351	sugar:hydrogen symporter activity	GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR001127 InterPro:IPR001996 InterPro:IPR003352 SP_KW:KW-0762	F	Seeded from EcoCyc	complete
	GO:0005886	plasma membrane	GO_REF:0000004 GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037	C	Seeded from EcoCyc	complete
	GO:0006810	transport	GO_REF:0000002 GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR001127 InterPro:IPR001996 SP_KW:KW-0813	P	Seeded from EcoCyc	complete
	GO:0016052	carbohydrate catabolic process				P	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0006464	protein modification process				P	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0016485	protein processing				P	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0008643	carbohydrate transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0762	P	Seeded from EcoCyc	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
Protein	Subunits of EIIBgl	could be indirect
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Notes
plasma membrane	C-terminus localized in the cytoplasm with 10 predicted transmembrane domains	Daley et al. (2005) ^[7]
plasma membrane			From EcoCyc^[3]
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence	at EcoCyc MTELARKIVA GVGGADNIVS LMHCATRLRF KLKDESKAQA EVLKKTPGII MVVESGGQFQ VVIGNHVADV FLAVNSVAGL DEKAQQAPEN DDKGNLLNRF VYVISGIFTP LIGLMAATGI LKGMLALALT FQWTTEQSGT YLILFSASDA LFWFFPIILG YTAGKRFGGN PFTAMVIGGA LVHPLILTAF ENGQKADALG LDFLGIPVTL LNYSSSVIPI IFSAWLCSIL ERRLNAWLPS AIKNFFTPLL CLMVITPVTF LLVGPLSTWI SELIAAGYLW LYQAVPAFAG AVMGGFWQIF VMFGLHWGLV PLCINNFTVL GYDTMIPLLM PAIMAQVGAA LGVFLCERDA QKKVVAGSAA LTSLFGITEP AVYGVNLPRK YPFVIACISG ALGATIIGYA QTKVYSFGLP SIFTFMQTIP STGIDFTVWA SVIGGVIAIG CAFVGTVMLH FITAKRQPAQ GAPQEKTPEV ITPPEQGGIC SPMTGEIVPL IHVADTTFAS GLLGKGIAIL PSVGEVRSPV AGRIASLFAT LHAIGIESDD GVEILIHVGI DTVKLDGKFF SAHVNVGDKV NTGDRLISFD IPAIREAGFD LTTPVLISNS DDFTDVLPHG TAQISAGEPL LSIIR
Length	625
Mol. Wt	66.48 kDa (calc) ^[2]
pI
Extinction coefficient	65890 - 66890 (calc based on 11 Y, 9 W, and 8 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes
Domain	1 - 84	PTS EIIB type-1	UniProt:P08722
Domain	102 - 465	PTS EIIC type-1	UniProt:P08722
Domain	495 - 599	PTS EIIA type-1	UniProt:P08722
Domain	426 - 448	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	100 - 119	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	139 - 161	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	168 - 190	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	205 - 227	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	234 - 256	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	260 - 282	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	287 - 309	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	324 - 346	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	381 - 400	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
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<motif_map/>

Click the image to view raw output from TMHMM.

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

Models

View models at:

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:BGLF-MONOMER
SwissModel (EcoliWiki Page)	SwissModel:P08722
UniProt (EcoliWiki Page)	UniProt:P08722
PFAM (EcoliWiki Page)	PFAM:PF00367
RefSeq (EcoliWiki Page)	RefSeq:NP_418178
ModBase (EcoliWiki Page)	ModBase:P08722
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Notes

Links

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Name	URL	Comments
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References

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↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 ^5.8 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
↑ ^8.00 ^8.01 ^8.02 ^8.03 ^8.04 ^8.05 ^8.06 ^8.07 ^8.08 ^8.09 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed

bglF:Gene Product(s): Difference between revisions

Revision as of 22:40, 21 May 2009

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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@@ Line 304: / Line 304: @@
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 C
+|
+Seeded from EcoCyc
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+complete
+|-
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+GO:0006810
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+transport
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+GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
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+IEA: Inferred from Electronic Annotation
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+InterPro:IPR001127<br />InterPro:IPR001996<br />SP_KW:KW-0813
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+P
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 Seeded from EcoCyc
@@ Line 369: / Line 388: @@
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-GO:0006810
+GO:0008643
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-transport
+carbohydrate transport
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-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
+GO_REF:0000004
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 IEA: Inferred from Electronic Annotation
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-InterPro:IPR001127<br />InterPro:IPR001996<br />SP_KW:KW-0813
+SP_KW:KW-0762
 |
 P

bglF:Gene Product(s): Difference between revisions

Revision as of 22:40, 21 May 2009

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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