umuD:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''umuD''  
''umuD''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK1171, b1183, JW1172, uvm''<ref name='LIB:Riley_2006'/>
''ECK1171, b1183, JW1172, uvm''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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DNA polymerase V subunit, capable of translesion synthesis; inducible mutagenesis; error-prone repair; UmuDC single-stranded binding protein with RecA-coated DNA; intrinsic AP lyase activity<ref name='LIB:EcoGene'/>
DNA polymerase V subunit, capable of translesion synthesis; inducible mutagenesis; error-prone repair; UmuDC single-stranded binding protein with RecA-coated DNA; intrinsic AP lyase activity<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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DNA polymerase V, subunit D<ref name='LIB:Riley_2006'/>, B1183<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UmuD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
DNA polymerase V, subunit D<ref name='LIB:Riley_2006'/>, B1183<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UmuD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:umuDC|umuDC]]<ref name='LIB:EcoCyc10.6'/>, OP00250  
transcription unit(s): [[:Category:Txn_unit:umuDC|umuDC]]<ref name='LIB:EcoCyc10.6'/>, OP00250  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 01:07, 10 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

umuD

Gene Synonym(s)

ECK1171, b1183, JW1172, uvm[1]

Product Desc.

SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC[2][3];

Component of DNA polymerase V[3]

DNA polymerase V subunit, capable of translesion synthesis; inducible mutagenesis; error-prone repair; UmuDC single-stranded binding protein with RecA-coated DNA; intrinsic AP lyase activity[4]

Product Synonyms(s)

DNA polymerase V, subunit D[1], B1183[2][1], UmuD[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): umuDC[2], OP00250

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


LexA regulon. Autocleavage removes the first 24 amino acids to form UmuD', required for mutageneic translesion synthesis (TLS). UmuD and UmuD' are intrinsiclly disordered proteins (IDPs) that can nonetheless form stable dimers (Simon, 2008).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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