ruvA:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''ruvA''  
''ruvA''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK1862, b1861, JW1850''<ref name='LIB:Riley_2006'/>
''ECK1862, b1861, JW1850''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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branch migration of Holliday structures; repair<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
branch migration of Holliday structures; repair<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Holliday junction recognition factor, recruits RuvB; works in conjunction with RuvB helicase to drive branch migration during recombination<ref name='LIB:EcoGene'/>
Holliday junction recognition factor, recruits RuvB; works in conjunction with RuvB helicase to drive branch migration during recombination<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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component of RuvABC resolvasome, regulatory subunit<ref name='LIB:Riley_2006'/>, B1861<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RuvA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
component of RuvABC resolvasome, regulatory subunit<ref name='LIB:Riley_2006'/>, B1861<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RuvA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:ruvAB|ruvAB]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:ruvAB|ruvAB]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 05:52, 9 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

ruvA

Gene Synonym(s)

ECK1862, b1861, JW1850[1]

Product Desc.

branch migration of Holliday structures; repair[2][3];

Component of resolvasome[2][3]

Holliday junction recognition factor, recruits RuvB; works in conjunction with RuvB helicase to drive branch migration during recombination[4]

Product Synonyms(s)

component of RuvABC resolvasome, regulatory subunit[1], B1861[2][1], RuvA[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ruvAB[2]

Regulation/Activity


See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Binds Holliday junction as two tetramers (an octamer) and each tetrameric half recruits one RuvB hexameric helicase. RuvAB may also directly convert replication forks into Holliday junctions. Required for replication forks reversal in certain replication mutants. LexA regulon. RuvA may be a sliding collar that protects Holliday junctions from unwinding while promoting branch migration[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.