lepA:Quickview: Difference between revisions
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{| | {| id="G49aeeaec7bc56" class=" tableEdit New_Quickview_Table" | ||
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!align=left | !align=left |Standard Name | ||
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''lepA'' | ''lepA'' | ||
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!align=left | !align=left |Gene Synonym(s) | ||
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''ECK2567, b2569, JW2553''<ref name='LIB:Riley_2006'/> | ''ECK2567, b2569, JW2553''<ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left |Product Desc. | ||
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GTP-binding membrane protein<ref name='LIB:EcoCyc10.6'/>; elongation factor 4<ref name='LIB:EcoCyc11.1'/> | GTP-binding membrane protein<ref name='LIB:EcoCyc10.6'/>; elongation factor 4<ref name='LIB:EcoCyc11.1'/> | ||
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Back-translocating Elongation Factor EF4, GTPase; required for efficient and accurate protein synthesis<ref name='LIB:EcoGene'/> | Back-translocating Elongation Factor EF4, GTPase; required for efficient and accurate protein synthesis<ref name='LIB:EcoGene'/> | ||
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!align=left | !align=left |Product Synonyms(s) | ||
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GTP-binding membrane protein<ref name='LIB:Riley_2006'/>, B2569<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, LepA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, EF4<ref name='LIB:EcoCyc11.1'/><ref name='LIB:Riley_2006'/> | GTP-binding membrane protein<ref name='LIB:Riley_2006'/>, B2569<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, LepA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, EF4<ref name='LIB:EcoCyc11.1'/><ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left |Knock-Out Phenotype | ||
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!align=left | !align=left |Regulation/Expression | ||
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transcription unit(s): [[:Category:Txn_unit:lepAB|lepAB]]<ref name='LIB:EcoCyc10.6'/> | transcription unit(s): [[:Category:Txn_unit:lepAB|lepAB]]<ref name='LIB:EcoCyc10.6'/> | ||
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!align=left | !align=left |Regulation/Activity | ||
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Revision as of 01:54, 9 January 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
lepA |
|---|---|
| Gene Synonym(s) |
ECK2567, b2569, JW2553[1] |
| Product Desc. |
GTP-binding membrane protein[2]; elongation factor 4[3] Back-translocating Elongation Factor EF4, GTPase; required for efficient and accurate protein synthesis[4] |
| Product Synonyms(s) |
GTP-binding membrane protein[1], B2569[2][1], LepA[2][1], EF4[3][1] |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
Although EF4 improves translational accuracy, it can not reverse paromomycin-induced errors (Qin, 2006). EF4 is a widely conserved protein, the first four domains are related to EF-G domains I, II, III, and V (Qin, 2006). EF4 overexpression is toxic (Qin 2006). EF4 (LepA) is in the lepAB operon but has no known role in signal peptidase I (LepB) activity.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.