dinB:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''dinB''  
''dinB''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK0232, b0231, JW0221, dinP''<ref name='LIB:Riley_2006'/>
''ECK0232, b0231, JW0221, dinP''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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DNA polymerase IV (Y-family DNA polymerase; translesion DNA synthesis)<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
DNA polymerase IV (Y-family DNA polymerase; translesion DNA synthesis)<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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DNA polymerase IV, capable of translesion synthesis; overexpression enhances mutagenesis; mediates targeted mutagenesis by 4-NQO; intrinsic AP lyase activity<ref name='LIB:EcoGene'/>
DNA polymerase IV, capable of translesion synthesis; overexpression enhances mutagenesis; mediates targeted mutagenesis by 4-NQO; intrinsic AP lyase activity<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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DNA polymerase IV<ref name='LIB:Riley_2006'/>, B0231<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DinB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DinP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
DNA polymerase IV<ref name='LIB:Riley_2006'/>, B0231<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DinB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DinP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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Sensitivity to 4-NQO <ref name=PMID:16407906/>
Sensitivity to 4-NQO <ref name=PMID:16407906/>
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:dinB|dinB]]<ref name='LIB:EcoCyc10.6'/> [[:Category:Txn_unit:dinB|dinB yafNOP]]<ref name=PMID:11333217/>  
transcription unit(s): [[:Category:Txn_unit:dinB|dinB]]<ref name='LIB:EcoCyc10.6'/> [[:Category:Txn_unit:dinB|dinB yafNOP]]<ref name=PMID:11333217/>  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 00:38, 9 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

dinB

Gene Synonym(s)

ECK0232, b0231, JW0221, dinP[1]

Product Desc.

DNA polymerase IV (Y-family DNA polymerase; translesion DNA synthesis)[2][3]

DNA polymerase IV, capable of translesion synthesis; overexpression enhances mutagenesis; mediates targeted mutagenesis by 4-NQO; intrinsic AP lyase activity[4]

Product Synonyms(s)

DNA polymerase IV[1], B0231[2][1], DinB[2][1], DinP[2][1]

Knock-Out Phenotype

Sensitivity to 4-NQO [5]

Regulation/Expression

transcription unit(s): dinB[2] dinB yafNOP[6]

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Part of dinB-yafNOP operon. LexA regulon. The phenotype of some dinB alleles to reduce spontaneous mutations may be due to polarity effects.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Jarosz, DF et al. (2006) A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates. Nature 439 225-8 PubMed
  6. ↑ Courcelle, J et al. (2001) Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli. Genetics 158 41-64 PubMed
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