dinB:Quickview
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
dinB |
|---|---|
| Gene Synonym(s) |
ECK0232, b0231, JW0221, dinP[1], dinP |
| Product Desc. |
DNA polymerase IV (Y-family DNA polymerase; translesion DNA synthesis)[2][3] DNA polymerase IV, capable of translesion synthesis; overexpression enhances mutagenesis; mediates targeted mutagenesis by 4-NQO; intrinsic AP lyase activity[4] |
| Product Synonyms(s) |
DNA polymerase IV[1], B0231[2][1], DinB[2][1], DinP[2][1] , dinP, ECK0232, JW0221, b0231 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype |
Sensitivity to 4-NQO [5] |
| Regulation/Expression |
transcription unit(s): dinB[2] dinB yafNOP[6] |
| Regulation/Activity | |
| Quick Links |
|
| edit table |
</protect> See Help:Quickview for help with entering information in the Quickview table. <protect></protect>
Notes
Part of dinB-yafNOP operon. LexA regulon. The phenotype of some dinB alleles to reduce spontaneous mutations may be due to polarity effects.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Jarosz, DF et al. (2006) A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates. Nature 439 225-8 PubMed
- ↑ Courcelle, J et al. (2001) Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli. Genetics 158 41-64 PubMed
