dinB:Quickview: Difference between revisions
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!align=left {{table_heading_style}} |Standard Name | !align=left {{table_heading_style}} |Standard Name | ||
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''dinB'' | |||
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!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK0232, b0231, JW0221, dinP''<ref name='LIB:Riley_2006'/> | |||
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!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
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DNA polymerase IV (Y-family DNA polymerase; translesion DNA synthesis)<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | |||
DNA polymerase IV, capable of translesion synthesis; overexpression enhances mutagenesis; mediates targeted mutagenesis by 4-NQO; intrinsic AP lyase activity<ref name='LIB:EcoGene'/> | |||
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!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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DNA polymerase IV<ref name='LIB:Riley_2006'/>, B0231<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DinB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DinP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | |||
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!align=left {{table_heading_style}} |Knock-Out Phenotype | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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Sensitivity to 4-NQO <ref name=PMID:16407906/> | |||
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!align=left {{table_heading_style}} |Regulation/Expression | !align=left {{table_heading_style}} |Regulation/Expression | ||
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transcription unit(s): [[:Category:Txn_unit:dinB|dinB]]<ref name='LIB:EcoCyc10.6'/> [[:Category:Txn_unit:dinB|dinB yafNOP]]<ref name=PMID:11333217/> | |||
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!align=left {{table_heading_style}} |Regulation/Activity | !align=left {{table_heading_style}} |Regulation/Activity | ||
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Revision as of 20:25, 4 March 2009
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
dinB |
|---|---|
| Gene Synonym(s) |
ECK0232, b0231, JW0221, dinP[1] |
| Product Desc. |
DNA polymerase IV (Y-family DNA polymerase; translesion DNA synthesis)[2][3] DNA polymerase IV, capable of translesion synthesis; overexpression enhances mutagenesis; mediates targeted mutagenesis by 4-NQO; intrinsic AP lyase activity[4] |
| Product Synonyms(s) | |
| Knock-Out Phenotype |
Sensitivity to 4-NQO [5] |
| Regulation/Expression |
transcription unit(s): dinB[2] dinB yafNOP[6] |
| Regulation/Activity |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
Part of dinB-yafNOP operon. LexA regulon. The phenotype of some dinB alleles to reduce spontaneous mutations may be due to polarity effects.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Jarosz, DF et al. (2006) A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates. Nature 439 225-8 PubMed
- ↑ Courcelle, J et al. (2001) Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli. Genetics 158 41-64 PubMed