groL:Quickview: Difference between revisions

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Adding EcoGene Comments
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!align=left {{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[groL:Gene|''groL]]'' (synonyms: ''ECK4137, b4143, JW4103, groEL, mopB, groE, hdh, mopA, tabB'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left {{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[groL:Gene_Product(s)|GroL product]]<ref name='LIB:Riley_2006'/>: Cpn60 chaperonin GroEL, large subunit of GroESL product, B4143 product, Hdh product, TabB product, MopA product, GroEL product
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!align=left {{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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GroEL, chaperone Hsp60, peptide-dependent ATPase, heat shock protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
!align=left {{table_heading_style}} |Product Synonyms(s)
 
Component of [[:Category:Complex:GroEL-GroES Chaperonin-CPLX|GroEL-GroES Chaperonin-CPLX]]<ref name='LIB:EcoCyc11.1'/>
 
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:groS|groS]]<ref name='LIB:EcoCyc10.6'/>, groS, groES
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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Revision as of 20:43, 4 March 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name
Gene Synonym(s)
Product Desc.
Product Synonyms(s)
Knock-Out Phenotype
Regulation/Expression
Regulation/Activity
edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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groL is an essential gene. GroEL binds and regulates rpoH. Cells deficient in GroEL and GroES lyse due to inability to produce cell wall as a result of the reduced level of DapA, the first enzyme in the DAP synthesis pathway. Growth below 8C is impaired due to GroESL inactivation and can be rescued by transgenic Oleispira antarctica Cpn10/60. Overproduction of GroESL can supress tig/dnaK synthetic lethality at 30 degrees C.[1]



References

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  1. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.