deoR:Quickview: Difference between revisions
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The ''deoR'' gene is found immediately upstream of the operon. ''DeoR'' encodes a repressor protein that negatively regulates the expression of the operon at the level of transcription. A ''deoR''-deficient mutant has a high level of ''deoxyriboaldolase'' and ''pyrimidine nucleoside phosphorylase''. <ref name='PMID:10074062'/> In ''deoR'' mutations, the repressor is absent and the colonies of the mutants grow more rapidly (Munch-Peterson, et al, Eur. J. Biochem 27: 208-215 (1972)). | The ''deoR'' gene is found immediately upstream of the operon. ''DeoR'' encodes a repressor protein that negatively regulates the expression of the operon at the level of transcription. A ''deoR''-deficient mutant has a high level of ''deoxyriboaldolase'' and ''pyrimidine nucleoside phosphorylase''. <ref name='PMID:10074062'/> In ''deoR'' mutations, the repressor is absent and the colonies of the mutants grow more rapidly (Munch-Peterson, et al, Eur. J. Biochem 27: 208-215 (1972)). | ||
Revision as of 23:21, 13 February 2009
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Gene Name | |
|---|---|
| Product(s) |
DeoR product[1]: DNA-binding transcriptional repressor product, B0840 product, NucR product, transcriptional repressor for deo operon, tsx, nupG product |
| Description | |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
The deoR gene is found immediately upstream of the operon. DeoR encodes a repressor protein that negatively regulates the expression of the operon at the level of transcription. A deoR-deficient mutant has a high level of deoxyriboaldolase and pyrimidine nucleoside phosphorylase. [4] In deoR mutations, the repressor is absent and the colonies of the mutants grow more rapidly (Munch-Peterson, et al, Eur. J. Biochem 27: 208-215 (1972)).
References
- ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Zeng, X & Saxild, HH (1999) Identification and characterization of a DeoR-specific operator sequence essential for induction of dra-nupC-pdp operon expression in Bacillus subtilis. J. Bacteriol. 181 1719-27 PubMed