metB:Gene Product(s): Difference between revisions

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** [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.48 2.5.1.48]<ref name='LIB:Riley_2006'/>
** [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.48 2.5.1.48]<ref name='LIB:Riley_2006'/>
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could be indirect   
could be indirect   
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!Compartment!!Description!!Evidence!!Notes
!Compartment!!Description!!Evidence!!Notes
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25900 - 26525 (calc based on 10 Y, 2 W, and 5 C residues)  
25900 - 26525 (calc based on 10 Y, 2 W, and 5 C residues)  
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!Type!!Residues!!Description!!Notes
!Type!!Residues!!Description!!Notes
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!Structure Type!!Organism!!Accession!!Residues covered!!Notes
!Structure Type!!Organism!!Accession!!Residues covered!!Notes
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!Resource type!!Source!!Notes/Reference
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Revision as of 09:32, 30 April 2008

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

MetB product

Synonyms

cystathionine gamma-synthase, PLP-dependent product[1], B3939 product[2][1], MetB product[2][1]

Product description

MetB[2][3];

Component of ; O-SUCCHOMOSERLYASE-CPLX[2]

EC number (for enzymes)
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See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Notes

Function

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Gene Ontology

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009063

amino acid catabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009086

methionine biosynthetic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

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See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Interactions

Partner Type Partner Notes

Protein

Subunits of O-SUCCHOMOSERLYASE-CPLX

could be indirect

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See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Notes

metB1 is a mutant brought about by X-ray mutagenesis and is most likely a deletion mutation.

The metB1 mutation causes a requirement for methionine and produces no enzymatic activity. [4]

Localization

Compartment Description Evidence Notes
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See Help:Product_localization for how to add or edit information in this section of EcoliWiki.


Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc 

MTRKQATIAV RSGLNDDEQY GCVVPPIHLS STYNFTGFNE PRAHDYSRRG NPTRDVVQRA
LAELEGGAGA VLTNTGMSAI HLVTTVFLKP GDLLVAPHDC YGGSYRLFDS LAKRGCYRVL
FVDQGDEQAL RAALAEKPKL VLVESPSNPL LRVVDIAKIC HLAREVGAVS VVDNTFLSPA
LQNPLALGAD LVLHSCTKYL NGHSDVVAGV VIAKDPDVVT ELAWWANNIG VTGGAFDSYL
LLRGLRTLVP RMELAQRNAQ AIVKYLQTQP LVKKLYHPSL PENQGHEIAA RQQKGFGAML
SFELDGDEQT LRRFLGGLSL FTLAESLGGV ESLISHAATM THAGMAPEAR AAAGISETLL
RISTGIEDGE DLIADLENGF RAANKG
Mol. Wt

41.55 kDa (calc) [2]

pI

6.43[2]

Extinction coefficient

25900 - 26525 (calc based on 10 Y, 2 W, and 5 C residues)

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See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Domains/Motifs/Modification Sites

Type Residues Description Notes
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Structure

Structure Type Organism Accession Residues covered Notes
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Notes

Gene Product Resources

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Resource type Source Notes/Reference
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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Notes

Accessions in Other Databases

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:O-SUCCHOMOSERLYASE-MONOMER

UniProt (EcoliWiki Page)

UniProt:P00935

PFAM (EcoliWiki Page)

PFAM:PF01053

RefSeq (EcoliWiki Page)

RefSeq:NP_418374

ModBase (EcoliWiki Page)

ModBase:P00935

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See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.

Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ Hall, BG (1989) Selection, adaptation, and bacterial operons. Genome 31 265-71 PubMed


Categories

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