lepA:Quickview: Difference between revisions
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[http://porteco.org/AjaxSearch.jsp?searchString=lepA&s=search PortEco search(lepA)] [http://ecoliwiki.net/tools/display_dna.php?gene=lepA&loc=MG1655:2705146..2703347,W3110:2705780..2703981,REL606:2628617..2626818,DH10B:2796911..2795112,BW2952:2589152..2590951 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2589152&end=2590951&gene=lepA&aa=mknirnfsiiahidhgkstlsdriiqicgglsdremeaqvldsmdlerergitikaqsvtldykasdgetyqlnfidtpghvdfsyevsrslaacegallvvdagqgveaqtlancytamemdlevvpvlnkidlpaadpervaeeiedivgidatdavrcsaktgvgvqdvlerlvrdipppegdpegplqaliidswfdnylgvvslirikngtlrkgdkvkvmstgqtynadrlgiftpkqvdrtelkcgevgwlvcaikdihgapvgdtltlarnpaekalpgfkkvkpqvyaglfpvssddyeafrdalgklslndaslfyepesssalgfgfrcgflgllhmeiiqerlereydldlittaptvvyevettsreviyvdspsklpavnniyelrepiaechmllpqaylgnvitlcvekrgvqtnmvyhgnqvaltyeipmaevvldffdrlkstsrgyasldynfkrfqasdmvrvdvlingervdalalithrdnsqnrgrelvekmkdliprqqfdiaiqaaigthiiarstvkqlrknvlakcyggdisrkkkllqkqkegkkrmkqignvelpqeaflailhvgkdnk Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=lepA+AND+escherichia+coli Pubmed(lepA)] [http:// | [http://porteco.org/AjaxSearch.jsp?searchString=lepA&s=search PortEco search(lepA)] [http://ecoliwiki.net/tools/display_dna.php?gene=lepA&loc=MG1655:2705146..2703347,W3110:2705780..2703981,REL606:2628617..2626818,DH10B:2796911..2795112,BW2952:2589152..2590951 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2589152&end=2590951&gene=lepA&aa=mknirnfsiiahidhgkstlsdriiqicgglsdremeaqvldsmdlerergitikaqsvtldykasdgetyqlnfidtpghvdfsyevsrslaacegallvvdagqgveaqtlancytamemdlevvpvlnkidlpaadpervaeeiedivgidatdavrcsaktgvgvqdvlerlvrdipppegdpegplqaliidswfdnylgvvslirikngtlrkgdkvkvmstgqtynadrlgiftpkqvdrtelkcgevgwlvcaikdihgapvgdtltlarnpaekalpgfkkvkpqvyaglfpvssddyeafrdalgklslndaslfyepesssalgfgfrcgflgllhmeiiqerlereydldlittaptvvyevettsreviyvdspsklpavnniyelrepiaechmllpqaylgnvitlcvekrgvqtnmvyhgnqvaltyeipmaevvldffdrlkstsrgyasldynfkrfqasdmvrvdvlingervdalalithrdnsqnrgrelvekmkdliprqqfdiaiqaaigthiiarstvkqlrknvlakcyggdisrkkkllqkqkegkkrmkqignvelpqeaflailhvgkdnk Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=lepA+AND+escherichia+coli Pubmed(lepA)] [http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=lepA Textpresso(lepA)] | ||
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Revision as of 18:20, 27 June 2011
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
lepA |
|---|---|
| Gene Synonym(s) |
ECK2567, b2569, JW2553[1] |
| Product Desc. |
GTP-binding membrane protein[2]; elongation factor 4[3] Back-translocating Elongation Factor EF4, GTPase; required for efficient and accurate protein synthesis[4] |
| Product Synonyms(s) |
GTP-binding membrane protein[1], B2569[2][1], LepA[2][1], EF4[3][1] |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
PortEco search(lepA) DNA display Protein display Pubmed(lepA) Textpresso(lepA) |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
Although EF4 improves translational accuracy, it can not reverse paromomycin-induced errors (Qin, 2006). EF4 is a widely conserved protein, the first four domains are related to EF-G domains I, II, III, and V (Qin, 2006). EF4 overexpression is toxic (Qin 2006). EF4 (LepA) is in the lepAB operon but has no known role in signal peptidase I (LepB) activity.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.