ftsK:Quickview: Difference between revisions
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essential cell division protein FtsK<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | essential cell division protein FtsK <ref name='PMID:9723913'/><ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | ||
Component of [[:Category:Complex:Xer site-specific recombination system|Xer site-specific recombination system]]<ref name='LIB:EcoCyc11.1'/> | Component of [[:Category:Complex:Xer site-specific recombination system|Xer site-specific recombination system]]<ref name='LIB:EcoCyc11.1'/> | ||
Revision as of 20:55, 10 June 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
ftsK |
|---|---|
| Gene Synonym(s) |
ECK0881, b0890, JW0873, dinH[1] |
| Product Desc. |
essential cell division protein FtsK [2][3][4]; Component of Xer site-specific recombination system[4] DNA translocase at septal ring sorting daughter chromsomes[5] |
| Product Synonyms(s) |
DNA-binding membrane protein required for chromosome resolution and partitioning[1], B0890[3][1], DinH[3][1], FtsK[3][1] |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype |
ts mutants filament |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
FtsK is required for resolution of chromosome dimers at dif by XerCD. FtsK helps keep the nucleoids properly localized, recognizing opposing replichores by using FtsK orienting polar sequences (KOPS). The N-terminal domain is membrane-anchored, localizes to the division septum and is required for cell division. The C-terminal domain has the non-essential translocase activity, which becomes essential for replicating the asymmetric replichores produced by chromosome inversion (Lesterlin, 2008). LexA regulon. Homologous to B. subtilis SpoIIIE protein. The ftsK gene is essential. The filamentous growth of mutants is suppressed by dacA deletions. ftsK44(ts) can be suppressed by an ftsA R286W mutation or by an ftsQAZ plasmid. Divisome.[5]
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ Wang, L & Lutkenhaus, J (1998) FtsK is an essential cell division protein that is localized to the septum and induced as part of the SOS response. Mol. Microbiol. 29 731-40 PubMed
- ↑ 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 5.0 5.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.