umuD:Quickview: Difference between revisions
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!align=left | !align=left {{table_heading_style}} |Standard Name | ||
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''umuD'' | ''umuD'' | ||
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!align=left | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK1171, b1183, JW1172, uvm''<ref name='LIB:Riley_2006'/> | ''ECK1171, b1183, JW1172, uvm''<ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Desc. | ||
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SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | ||
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DNA polymerase V subunit, capable of translesion synthesis; inducible mutagenesis; error-prone repair; UmuDC single-stranded binding protein with RecA-coated DNA; intrinsic AP lyase activity<ref name='LIB:EcoGene'/> | DNA polymerase V subunit, capable of translesion synthesis; inducible mutagenesis; error-prone repair; UmuDC single-stranded binding protein with RecA-coated DNA; intrinsic AP lyase activity<ref name='LIB:EcoGene'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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DNA polymerase V, subunit D<ref name='LIB:Riley_2006'/>, B1183<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UmuD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | DNA polymerase V, subunit D<ref name='LIB:Riley_2006'/>, B1183<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UmuD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Function from GO | ||
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'''Biological Process''' | |||
* GO:0006974 response to DNA damage stimulus ([http://www.geneontology.org/GO.evidence.shtml IEP]) | |||
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!align=left | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | |||
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transcription unit(s): [[:Category:Txn_unit:umuDC|umuDC]]<ref name='LIB:EcoCyc10.6'/>, OP00250 | transcription unit(s): [[:Category:Txn_unit:umuDC|umuDC]]<ref name='LIB:EcoCyc10.6'/>, OP00250 | ||
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!align=left | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[http://ecoliwiki.net/tools/display_dna.php?gene=umuD&loc=MG1655:1229990..1230409,W3110:1232344..1232763,DH10B:1270231..1270650,REL606:1230917..1231336 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1230917&end=1231336&gene=umuD&aa=mlfikpadlreivtfplfsdlvqcgfpspaadyveqridlnqlliqhpsatyfvkasgdsmidggisdgdllivdsaitashgdiviaavdgeftvkklqlrptvqlipmnsayspitissedtldvfgvvihvvkamr Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=umuD+AND+escherichia+coli Pubmed(umuD)] [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=umuD Textpresso(umuD)] | |||
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Revision as of 23:25, 21 January 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
umuD |
|---|---|
| Gene Synonym(s) |
ECK1171, b1183, JW1172, uvm[1] |
| Product Desc. |
SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC[2][3]; Component of DNA polymerase V[3] DNA polymerase V subunit, capable of translesion synthesis; inducible mutagenesis; error-prone repair; UmuDC single-stranded binding protein with RecA-coated DNA; intrinsic AP lyase activity[4] |
| Product Synonyms(s) | |
| Function from GO |
Biological Process
|
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
LexA regulon. Autocleavage removes the first 24 amino acids to form UmuD', required for mutageneic translesion synthesis (TLS). UmuD and UmuD' are intrinsiclly disordered proteins (IDPs) that can nonetheless form stable dimers (Simon, 2008).[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.