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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''tolA''  
''tolA''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK0728, b0739, JW0729, cim, excC, lky, tol-2''<ref name='LIB:Riley_2006'/>
''ECK0728, b0739, JW0729, cim, excC, lky, tol-2''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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TolA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
TolA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Tolerance to group A colicins, single-stranded filamentous DNA phage; required for OM integrity; membrane protein; bacteriocin tolerant<ref name='LIB:EcoGene'/>
Tolerance to group A colicins, single-stranded filamentous DNA phage; required for OM integrity; membrane protein; bacteriocin tolerant<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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membrane anchored protein in TolA-TolQ-TolR complex<ref name='LIB:Riley_2006'/>, B0739<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Lky<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Cim<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ExcC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TolA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
membrane anchored protein in TolA-TolQ-TolR complex<ref name='LIB:Riley_2006'/>, B0739<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Lky<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Cim<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ExcC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TolA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Cellular Component'''
* GO:0005886 plasma membrane ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0016021 integral to membrane ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Biological Process'''
* GO:0017038 protein import ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0043213 bacteriocin transport ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Molecular Function'''
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:ybgC-tolQRA|ybgC-tolQRA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:ybgC-tolQRA|ybgC-tolQRA]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=tolA&loc=MG1655:775565..776830,W3110:776764..778029,DH10B:828157..829422,REL606:757224..758489 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=757224&end=758489&gene=tolA&aa=mskateqndklkraiiisavlhvilfaaliwssfdenieasagggggssidavmvdsgavveqykrmqsqessakrsdeqrkmkeqqaaeelrekqaaeqerlkqlekerlaaqeqkkqaeeaakqaelkqkqaeeaaakaaadakakaeadakaaeeaakkaaadakkkaeaeaakaaaeaqkkaeaaaaalkkkaeaaeaaaaearkkaateaaekakaeaekkaaaekaaadkkaaaekaaadkkaaekaaaekaaadkkaaaekaaadkkaaaakaaaekaaaakaaaeaddifgelssgknapktgggakgnnaspagsgntknngasgadinnyagqiksaieskfydassyagktctlriklapdgmlldikpeggdpalcqaalaaaklakipkppsqavyevfknapldfkp Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=tolA+AND+escherichia+coli Pubmed(tolA)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=tolA Textpresso(tolA)]


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Revision as of 23:28, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

tolA

Gene Synonym(s)

ECK0728, b0739, JW0729, cim, excC, lky, tol-2[1]

Product Desc.

TolA[2][3];

Component of Tol-Pal Cell Envelope Complex[2]; The Tol-Pal Cell Envelope Complex[3]; The Colicin A Import System[3]; Colicin S4 Transport System[3]

Tolerance to group A colicins, single-stranded filamentous DNA phage; required for OM integrity; membrane protein; bacteriocin tolerant[4]

Product Synonyms(s)

membrane anchored protein in TolA-TolQ-TolR complex[1], B0739[2][1], Lky[2][1], Cim[2][1], ExcC[2][1], TolA[2][1]

Function from GO

Cellular Component

Biological Process

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ybgC-tolQRA[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(tolA)    Textpresso(tolA)

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See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Cell envelope integrity is stabilized by the Tol-Pal system linking inner and outer membranes. Mutants have elevated OM vesiculation (McBroom, 2006).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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