tolA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
tolA |
|---|---|
| Gene Synonym(s) |
ECK0728, b0739, JW0729, cim, excC, lky, tol-2[1] |
| Product Desc. |
Component of Tol-Pal Cell Envelope Complex[2]; The Tol-Pal Cell Envelope Complex[3]; The Colicin A Import System[3]; Colicin S4 Transport System[3] Tolerance to group A colicins, single-stranded filamentous DNA phage; required for OM integrity; membrane protein; bacteriocin tolerant[4] |
| Product Synonyms(s) |
membrane anchored protein in TolA-TolQ-TolR complex[1], B0739[2][1], Lky[2][1], Cim[2][1], ExcC[2][1], TolA[2][1] , cim, ECK0728, excC, JW0729, lky, b0739 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): ybgC-tolQRA[2] |
| Regulation/Activity | |
| Quick Links |
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Notes
Cell envelope integrity is stabilized by the Tol-Pal system linking inner and outer membranes. Mutants have elevated OM vesiculation (McBroom, 2006).[4]
Phages can bind to the periplasmic domain of tolA and thus infect the cell (see Phage_f1). [5]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Edited by Richard Calendar (2006) The Bacteriophages (Oxford University Press, Oxford, NY) ISBN 0-19-514850-9
