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{{Tab On|Quickview|csrA}}{{Tab|Gene|csrA}}{{Tab|Gene Product(s)|csrA}}{{Tab|Expression|csrA}}{{Tab|Evolution|csrA}}{{Tab|On One Page|csrA}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[csrA:Gene|''csrA]]'' (synonyms: ''ECK2691, b2696, JW2666, zfiA'')<ref name='LIB:Riley_2006'/>
''csrA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[csrA:Gene_Product(s)|CsrA product]]<ref name='LIB:Riley_2006'/>: pleiotropic regulatory protein for carbon source metabolism product, B2696 product, ZfiA product
''ECK2691, b2696, JW2666, zfiA''<ref name='LIB:Riley_2006'/>, zfiA''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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carbon storage regulator; controls glycogen synthesis, gluconeogenesis, cell size and surface properties<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
carbon storage regulator; controls glycogen synthesis, gluconeogenesis, cell size and surface properties<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:CsrA complex with CsrB RNA|CsrA complex with CsrB RNA]]<ref name='LIB:EcoCyc11.1'/>
Component of [[:Category:Complex:CsrA complex with CsrB RNA|CsrA complex with CsrB RNA]]<ref name='LIB:EcoCyc11.1'/>


Global regulator of carbon source metabolism; CsrA exerts reciprocal effects on glycolysis versus gluconeogenesis and glycogen biosynthesis; glgC mRNA-binding activity blocks GlgC translation; csrB RNA inhibits csrA<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''pleiotropic regulatory protein for carbon source metabolism<ref name='LIB:Riley_2006'/>, B2696<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ZfiA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CsrA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2691, JW2666, zfiA, b2696''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:csrA|csrA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:csrA|csrA]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=csrA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11447]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001410&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=csrA&loc=MG1655%3A2817168..2816983,W3110%3A2817802..2817617,DH10B%3A2909710..2909525,REL606%3A2714005..2713820,BW2952%3A2702795..2702980]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2702795&end=2702980&gene=csrA&aa=mliltrrvgetlmigdevtvtvlgvkgnqvrigvnapkevsvhreeiyqriqaeksqqssy]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=csrA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=csrA]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
Recombinant CsrA-His6 was N-terminally sequenced, but this does not Verify since translation start was forced at ATG: Met is not clipped: MLIL start.  CsrA also postively regulates FlhCD post-translationally, and hence is required for motility.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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<references/>
<references/>
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Latest revision as of 21:52, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

csrA

Gene Synonym(s)

ECK2691, b2696, JW2666, zfiA[1], zfiA

Product Desc.

carbon storage regulator; controls glycogen synthesis, gluconeogenesis, cell size and surface properties[2][3];

Component of CsrA complex with CsrB RNA[3]

Global regulator of carbon source metabolism; CsrA exerts reciprocal effects on glycolysis versus gluconeogenesis and glycogen biosynthesis; glgC mRNA-binding activity blocks GlgC translation; csrB RNA inhibits csrA[4]

Product Synonyms(s)

pleiotropic regulatory protein for carbon source metabolism[1], B2696[2][1], ZfiA[2][1], CsrA[2][1] , ECK2691, JW2666, zfiA, b2696

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): csrA[2]

Regulation/Activity
Quick Links



        

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See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Recombinant CsrA-His6 was N-terminally sequenced, but this does not Verify since translation start was forced at ATG: Met is not clipped: MLIL start. CsrA also postively regulates FlhCD post-translationally, and hence is required for motility.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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