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{{Tab On|Quickview|ruvA}}{{Tab|Gene|ruvA}}{{Tab|Gene Product(s)|ruvA}}{{Tab|Expression|ruvA}}{{Tab|Evolution|ruvA}}{{Tab|On One Page|ruvA}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[ruvA:Gene|''ruvA]]'' (synonyms: ''ECK1862, b1861, JW1850'')<ref name='LIB:Riley_2006'/>
''ruvA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[ruvA:Gene_Product(s)|RuvA product]]<ref name='LIB:Riley_2006'/>: component of RuvABC resolvasome, regulatory subunit product, B1861 product
''ECK1862, b1861, JW1850''<ref name='LIB:Riley_2006'/>, JW1850''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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branch migration of Holliday structures; repair<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
branch migration of Holliday structures; repair<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:resolvasome|resolvasome]]<ref name='LIB:EcoCyc10.6'/>
Component of [[:Category:Complex:resolvasome|resolvasome]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Holliday junction recognition factor, recruits RuvB; works in conjunction with RuvB helicase to drive branch migration during recombination<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''component of RuvABC resolvasome, regulatory subunit<ref name='LIB:Riley_2006'/>, B1861<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RuvA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1862, JW1850, b1861''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:ruvAB|ruvAB]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:ruvAB|ruvAB]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=ruvA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=RUVA]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120004475&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=ruvA&loc=MG1655%3A1944000..1943389,W3110%3A1947690..1947079,DH10B%3A2034571..2033960,REL606%3A1924746..1924135,BW2952%3A1835448..1836059]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1835448&end=1836059&gene=ruvA&aa=migrlrgiiiekqpplvlievggvgyevhmpmtcfyelpeagqeaivfthfvvredaqllygfnnkqertlfkeliktngvgpklalailsgmsaqqfvnavereevgalvklpgigkktaerlivemkdrfkglhgdlftpaadlvltspaspatddaeqeavaalvalgykpqeasrmvskiarpdassetlirealraal]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=ruvA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=ruvA]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
Binds Holliday junction as two tetramers (an octamer) and each tetrameric half recruits one RuvB hexameric helicase. RuvAB may also directly convert replication forks into Holliday junctions. Required for replication forks reversal in certain replication mutants. LexA regulon. RuvA may be a sliding collar that protects Holliday junctions from unwinding while promoting branch migration<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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<references/>
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Latest revision as of 21:46, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

ruvA

Gene Synonym(s)

ECK1862, b1861, JW1850[1], JW1850

Product Desc.

branch migration of Holliday structures; repair[2][3];

Component of resolvasome[2][3]

Holliday junction recognition factor, recruits RuvB; works in conjunction with RuvB helicase to drive branch migration during recombination[4]

Product Synonyms(s)

component of RuvABC resolvasome, regulatory subunit[1], B1861[2][1], RuvA[2][1] , ECK1862, JW1850, b1861

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ruvAB[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


Binds Holliday junction as two tetramers (an octamer) and each tetrameric half recruits one RuvB hexameric helicase. RuvAB may also directly convert replication forks into Holliday junctions. Required for replication forks reversal in certain replication mutants. LexA regulon. RuvA may be a sliding collar that protects Holliday junctions from unwinding while promoting branch migration[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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