hipA:Quickview: Difference between revisions

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Quickview

Standard Name	hipA
Gene Synonym(s)	ECK1500, b1507, JW1500^[1], JW1500
Product Desc.	HipA Polypeptide^[2]; serine kinase HipA^[3]; Component of HipB transcriptional repressor^[3] Toxin, growth inhibition blocked by continuous HipB synthesis;; probable role in cell division^[4]
Product Synonyms(s)	regulator with hipB^[1], B1507^[2]^[1], HipA^[2]^[1] , ECK1500, JW1500, b1507
Function from GO	<GO_nr />
Knock-Out Phenotype
Regulation/Expression	transcription unit(s): hipBA^[2]
Regulation/Activity
Quick Links
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Notes

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HipA serine protein kinase autophosphorylates Ser150 and this activity is essential for persister formation (Correia, 2006). HipA binds and phosphorylates TufA/TufB (Schumacher, 2009).^[4]

References

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↑ ^1.0 ^1.1 ^1.2 ^1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^4.0 ^4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.

[LIB:Riley_2006-1] 1.0 ^1.1 ^1.2 ^1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)

[LIB:EcoCyc10.6-2] 2.0 ^2.1 ^2.2 ^2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7

[LIB:EcoCyc11.1-3] 3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7

[LIB:EcoGene-4] 4.0 ^4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.

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+-->{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
 <noinclude>{{TabsTop}}
 {{Tab On|Quickview|hipA}}{{Tab|Gene|hipA}}{{Tab|Gene Product(s)|hipA}}{{Tab|Expression|hipA}}{{Tab|Evolution|hipA}}{{Tab|On One Page|hipA}}{{TabsBottom}}
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+{|   id="J49aee8bee9d99"  class=" tableEdit New_Quickview_Table"
 |-
-!{{table_heading_style}} |Gene Name
+!align=left {{table_heading_style}} |Standard Name
-|
+||
-[[hipA:Gene|''hipA]]'' (synonyms: ''ECK1500, b1507, JW1500'')<ref name='LIB:Riley_2006'/>
+''hipA''
 |-
-!{{table_heading_style}} |Product(s)
+!align=left {{table_heading_style}} |Gene Synonym(s)
-|
+||
-[[hipA:Gene_Product(s)|HipA product]]<ref name='LIB:Riley_2006'/>: regulator with hipB product, B1507 product
+''ECK1500, b1507, JW1500''<ref name='LIB:Riley_2006'/>, JW1500''
 |-
-!{{table_heading_style}} |Description
+!align=left {{table_heading_style}} |Product Desc.
-|
+||
-HipA Polypeptide<ref name='LIB:EcoCyc10.6'/> serine kinase HipA<ref name='LIB:EcoCyc11.1'/>
+HipA Polypeptide<ref name='LIB:EcoCyc10.6'/>; serine kinase HipA<ref name='LIB:EcoCyc11.1'/>;
 Component of [[:Category:Complex:HipB transcriptional repressor|HipB transcriptional repressor]]<ref name='LIB:EcoCyc11.1'/>
+Toxin, growth inhibition blocked by continuous HipB synthesis;; probable role in cell division<ref name='LIB:EcoGene'/>
+|-
+!align=left {{table_heading_style}} |Product Synonyms(s)
+||
+''regulator with hipB<ref name='LIB:Riley_2006'/>, B1507<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HipA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1500, JW1500, b1507''
+|-
+!align=left {{table_heading_style}} |Function from GO
+||
+<GO_nr />
 |-
-!{{table_heading_style}} |Knock-Out Phenotype
+!align=left {{table_heading_style}} |Knock-Out Phenotype
-|
+||
 |-
-!{{table_heading_style}} |Regulation/Expression
+!align=left {{table_heading_style}} |Regulation/Expression
-|
+||
 transcription unit(s): [[:Category:Txn_unit:hipBA|hipBA]]<ref name='LIB:EcoCyc10.6'/>
 |-
-!{{table_heading_style}} |Regulation/Activity
+!align=left {{table_heading_style}} |Regulation/Activity
-|
+||
 |-
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+!align=left {{table_heading_style}} |Quick Links
+||
+[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=hipA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10443]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000436&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=hipA&loc=MG1655%3A1590200..1588878,W3110%3A1593890..1592568,DH10B%3A1679825..1678503,REL606%3A1568743..1567421,BW2952%3A1480937..1482259]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1480937&end=1482259&gene=hipA&aa=mpklvtwmnnqrvgeltklangahtfkyapewlasryarplslslplqrgnitsdavfnffdnllpdspivrdrivkryhaksrqpfdllseigrdsvgavtlipedetvthpimawekltearleevltaykadiplgmireendfrisvagaqektallrigndwcipkgitptthiiklpigeirqpnatldlsqsvdneyyclllakelglnvpdaeiikagnvralaverfdrrwnaertvllrlpqedmcqtfglpssvkyesdggpgiarimaflmgssealkdrydfmkfqvfqwligatdghaknfsvfiqaggsyrltpfydiisafpvlggtgihisdlklamglnaskgkktaidkiyprhflatakvlrfpevqmheilsdfarmipaaldnvktslptdfpenvvtavesnvlrlhgrlsreygsk]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hipA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=hipA]]&nbsp;&nbsp;
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+{{Quickview_table_help}}
 <protect><!--Quickview_notes--></protect>
-==Notes==
+===Notes===
+{{BacktoTop}}
+HipA serine protein kinase autophosphorylates Ser150 and this activity is essential for persister formation (Correia, 2006). HipA binds and phosphorylates TufA/TufB (Schumacher, 2009).<ref name='LIB:EcoGene'/>
 <noinclude>
 ==References==
+{{BacktoTop}}
 <references/>
 </noinclude>

hipA:Quickview: Difference between revisions

Latest revision as of 21:49, 27 May 2013

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