sbcD:Quickview: Difference between revisions

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{{Tab On|Quickview|sbcD}}{{Tab|Gene|sbcD}}{{Tab|Gene Product(s)|sbcD}}{{Tab|Expression|sbcD}}{{Tab|Evolution|sbcD}}{{Tab|On One Page|sbcD}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[sbcD:Gene|''sbcD]]'' (synonyms: ''ECK0392, b0398, JW0388, yajA'')<ref name='LIB:Riley_2006'/>
''sbcD''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[sbcD:Gene_Product(s)|SbcD product]]<ref name='LIB:Riley_2006'/>: exonuclease, dsDNA, ATP-dependent product, B0398 product, YajA product
''ECK0392, b0398, JW0388, yajA''<ref name='LIB:Riley_2006'/>, yajA''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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ATP-dependent dsDNA exonuclease<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
ATP-dependent dsDNA exonuclease<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:SbcCD ATP-dependent dsDNA exonuclease|SbcCD ATP-dependent dsDNA exonuclease]]<ref name='LIB:EcoCyc11.1'/>
Component of [[:Category:Complex:SbcCD ATP-dependent dsDNA exonuclease|SbcCD ATP-dependent dsDNA exonuclease]]<ref name='LIB:EcoCyc11.1'/>


DNA hairpin dsDNA 3'-exonuclease SbcCD, Mn(2+), ATP-dependent; ATP-independent 5' ssDNA endonuclease; cosuppressor with sbcB of recB recC mutations; heterodimeric<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''exonuclease, dsDNA, ATP-dependent<ref name='LIB:Riley_2006'/>, B0398<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YajA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SbcD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0392, JW0388, yajA, b0398''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:sbcC|sbcC]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:sbcC|sbcC]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=sbcD&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11094]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001082&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=sbcD&loc=MG1655%3A416176..414974,W3110%3A416176..414974,DH10B%3A355507..354305,REL606%3A385375..384173,BW2952%3A317733..318935]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=317733&end=318935&gene=sbcD&aa=mrilhtsdwhlgqnfysksreaehqafldwlletaqthqvdaiivagdvfdtgsppsyartlynrfvvnlqqtgchlvvlagnhdsvatlnesrdimaflnttvvasaghapqilprrdgtpgavlcpipflrprdiitsqaglngiekqqhllaaitdyyqqhyadacklrgdqplpiiatghlttvgasksdavrdiyigtldafpaqnfppadyialghihraqiiggmehvrycgspiplsfdecgkskyvhlvtfsngklesvenlnvpvtqpmavlkgdlasitaqleqwrdvsqeppvwldieittdeylhdiqrkiqalteslpvevllvrrsreqrervlasqqretlselsveevfnrrlaleeldesqqqrlqhlftttlhtlagehea]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=sbcD+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=sbcD]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
SbcCD can cleave dsDNA 5' ends sealed by a hairpin or by covalent linkage to a protein. SbcCD limits recombination between short inverted repeats, but is also reported to be required for palindrome-stimulated deletion. SbcCD protein forms a large 1.2 megadalton complex.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
{{BacktoTop}}
<references/>
<references/>
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Latest revision as of 21:46, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

sbcD

Gene Synonym(s)

ECK0392, b0398, JW0388, yajA[1], yajA

Product Desc.

ATP-dependent dsDNA exonuclease[2][3];

Component of SbcCD ATP-dependent dsDNA exonuclease[3]

DNA hairpin dsDNA 3'-exonuclease SbcCD, Mn(2+), ATP-dependent; ATP-independent 5' ssDNA endonuclease; cosuppressor with sbcB of recB recC mutations; heterodimeric[4]

Product Synonyms(s)

exonuclease, dsDNA, ATP-dependent[1], B0398[2][1], YajA[2][1], SbcD[2][1] , ECK0392, JW0388, yajA, b0398

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): sbcC[2]

Regulation/Activity
Quick Links



        

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


SbcCD can cleave dsDNA 5' ends sealed by a hairpin or by covalent linkage to a protein. SbcCD limits recombination between short inverted repeats, but is also reported to be required for palindrome-stimulated deletion. SbcCD protein forms a large 1.2 megadalton complex.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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