pdhR:Gene Product(s): Difference between revisions

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!align=left {{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
||
||
DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B0113<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YacB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GenA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PdhR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B0113<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YacB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GenA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PdhR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , aceC, ECK0112, genA, JW0109, yacB, b0113''
|-
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!align=left {{table heading style}} |Product description
!align=left {{table heading style}} |Product description
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|- {{table_heading_style}}
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-  
|-  
|
|


|
|
GO:0006350
GO:0003700
|
transcription factor activity
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000524
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0003700
|
transcription factor activity
|
PMID:2060763
|
ISS: Inferred from Sequence or Structural Similarity
|
UniProtKB:P10585<br />UniProtKB:P0A8V6<br />UniProtKB:P12380<br />UniProtKB:P22773
|
F
|
|
transcription
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0003700
|
transcription factor activity
|
|
PMID:7783622
PMID:7783622
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|
|
P
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0006350
GO:0003700
|
|
transcription
transcription factor activity
|
|
PMID:8057842
PMID:8057842
Line 111: Line 149:


|
|
P
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0006350
GO:0003700
|
|
transcription
transcription factor activity
|
|
PMID:8262214
PMID:8262214
|
|
IEP: Inferred from Expression Pattern
IDA: Inferred from Direct Assay
|
|


|
|
P
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0005622
|
intracellular
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000524
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0016563
|
transcription activator activity
|
PMID:2060763
|
ISS: Inferred from Sequence or Structural Similarity
|
UniProtKB:P10585<br />UniProtKB:P0A8V6<br />UniProtKB:P12380<br />UniProtKB:P22773
|
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0016564
GO:0016563
|
|
transcription repressor activity
transcription activator activity
|
|
PMID:7783622
PMID:7783622
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F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0016564
GO:0016563
|
|
transcription repressor activity
transcription activator activity
|
|
PMID:8057842
PMID:8057842
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F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0016564
GO:0016563
|
|
transcription repressor activity
transcription activator activity
|
|
PMID:8262214
PMID:8262214
|
|
IEP: Inferred from Expression Pattern
IDA: Inferred from Direct Assay
|
 
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
|


|
GO:0016566
|
specific transcriptional repressor activity
|
PMID:2060763
|
ISS: Inferred from Sequence or Structural Similarity
|
UniProtKB:P10585<br />UniProtKB:P0A8V6<br />UniProtKB:P12380<br />UniProtKB:P22773
|
|
F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0003677
GO:0016566
|
|
DNA binding
specific transcriptional repressor activity
|
|
GO_REF:0000004
PMID:7783622
|
|
IEA: Inferred from Electronic Annotation
IDA: Inferred from Direct Assay
|
|
SP_KW:KW-0238
 
|
|
F
F
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0003700
GO:0016566
|
|
transcription factor activity
specific transcriptional repressor activity
|
|
GO_REF:0000002
PMID:8057842
|
|
IEA: Inferred from Electronic Annotation
IDA: Inferred from Direct Assay
|
|
InterPro:IPR000524
 
|
|
F
F
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0005622
GO:0016566
|
|
intracellular
specific transcriptional repressor activity
|
|
GO_REF:0000002
PMID:8262214
|
|
IEA: Inferred from Electronic Annotation
IDA: Inferred from Direct Assay
|
|
InterPro:IPR000524
 
|
|
C
F
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0006350
GO:0032582
|
|
transcription
negative regulation of gene-specific transcription
|
|
GO_REF:0000004
PMID:2060763
|
|
IEA: Inferred from Electronic Annotation
ISS: Inferred from Sequence or Structural Similarity
|
|
SP_KW:KW-0804
UniProtKB:P10585<br />UniProtKB:P0A8V6<br />UniProtKB:P12380<br />UniProtKB:P22773
|
|
P
P
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0006355
GO:0032582
|
|
regulation of transcription, DNA-dependent
negative regulation of gene-specific transcription
|
|
GO_REF:0000002<br />GO_REF:0000004
PMID:7783622
|
|
IEA: Inferred from Electronic Annotation
IDA: Inferred from Direct Assay
|
|
InterPro:IPR000524<br />SP_KW:KW-0805
 
|
|
P
P
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0003677
GO:0032582
|
|
DNA binding
negative regulation of gene-specific transcription
|
|
GO_REF:0000004
PMID:8057842
|
|
IEA: Inferred from Electronic Annotation
IDA: Inferred from Direct Assay
|
|
SP_KW:KW-0238
 
|
|
F
P
|
|
Seeded from EcoCyc
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0003700
GO:0032582
|
|
transcription factor activity
negative regulation of gene-specific transcription
|
|
GO_REF:0000002
PMID:8262214
|
|
IEA: Inferred from Electronic Annotation
IDA: Inferred from Direct Assay
|
|
InterPro:IPR000524
 
|
|
F
P
|
|
Seeded from EcoCyc
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0005622
GO:0043193
|
|
intracellular
positive regulation of gene-specific transcription
|
|
GO_REF:0000002
PMID:2060763
|
|
IEA: Inferred from Electronic Annotation
ISS: Inferred from Sequence or Structural Similarity
|
|
InterPro:IPR000524
UniProtKB:P10585<br />UniProtKB:P0A8V6<br />UniProtKB:P12380<br />UniProtKB:P22773
|
|
C
P
|
|
Seeded from EcoCyc
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
|-  
|-  
|
|
 
|
|
GO:0006096
GO:0043193
|
|
glycolysis
positive regulation of gene-specific transcription
|
|
PMID:7783622
|
|
IDA: Inferred from Direct Assay
|
|
 
|
|
P  
P
|
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.  
Seeded from [[EcoCyc]] (v14.0)
|
|
required fields missing 
complete
|-  
|-  
|
|
 
|
|
GO:0005737
GO:0043193
|
|
cytoplasm
positive regulation of gene-specific transcription
|
|
PMID:8057842
|
|
IDA: Inferred from Direct Assay
|
|
 
|
|
C
P
|
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.  
Seeded from [[EcoCyc]] (v14.0)
|
|
required fields missing 
complete
|-  
|-  
|
|


|
|
GO:0006350
GO:0043193
|
|
transcription
positive regulation of gene-specific transcription
|
|
GO_REF:0000004<br />PMID:7783622<br />PMID:8057842<br />PMID:8262214
PMID:8262214
|
|
IEP: Inferred from Expression Pattern
IDA: Inferred from Direct Assay
|
|
SP_KW:KW-0804<br /><br /><br />
 
|
|
P
P
|
|
Seeded from EcoCyc
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  


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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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Experiment(s):EBI-1135589<br />  
Experiment(s):EBI-1135589<br />  


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!|Compartment!!Description!!Evidence!!Notes
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes


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!align=left {{table heading style}} |Name
||


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!align=left {{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
||
||
29.43 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
29.426 kDa
|-
|-
!align=left {{table heading style}} |pI
!align=left {{table heading style}} |pI
||
||
6.4 (calculated)
|-
|-
!align=left {{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
||
||
14440 - 14565 (calc based on 6 Y, 1 W, and 1 C residues)  
14,440 - 14,565 (calc based on 6 Y, 1 W, and 1 C residues)


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!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
11..74
|
[http://pfam.janelia.org/family/PF00392 PF00392  Bacterial regulatory proteins, gntR family]
|
 
|
PMID:19920124
|-  
|-  
|
|
Domain
Domain
|
|
9 - 77
99..227
|
[http://pfam.janelia.org/family/PF07729 PF07729  FCD domain]
|
|
[[interpro:IPR000524|HTH gntR-type]]
 
|
|
[http://www.uniprot.org/uniprot/P0ACL9#section_features UniProt:P0ACL9]
PMID:19920124


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</table>
</table>


<span id="Structure"></span><big>'''Structure'''</big>
<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
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{|   id="T46a731ff9154f" class=" tableEdit Product_structure_table"


|-
|-
!align=left {{table heading style}} |Structures
!align=left {{table heading style}} |Structures
||
||
<beststructure>pdhR
<beststructure>
562</beststructure>
gene=pdhR
 
taxon=562,83333
</beststructure>
|-
|-
!align=left {{table heading style}} |Models
!align=left {{table heading style}} |Models
||
||
View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=pdhR&sub=keywordSearc EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/P0ACL9 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=pdhR&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0ACL9 PSI-PRED (P0ACL9)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0ACL9 Genomes TO Protein (P0ACL9)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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===Notes===
===Notes===


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[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
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[http://www.ncbi.nlm.nih.gov/protein/16128106 GI:16128106]
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Escherichia coli str. K-12 substr. MG1655
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[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
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[http://www.ncbi.nlm.nih.gov/protein/NP_414655.1 GeneID:944827]
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Escherichia coli str. K-12 substr. MG1655
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[[ASAP]]
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[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11088-MONOMER EcoCyc:EG11088-MONOMER]
ASAP:ABE-0000394
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
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[http://www.uniprot.org/uniprot/P0ACL9 UniProtKB/Swiss-Prot:P0ACL9]
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Escherichia coli str. K-12 substr. MG1655
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[[EcoCyc]]
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EcoCyc:EG11088
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[[EcoGene]]
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EcoGene:EG11088
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
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[[uniprot:P0ACL9|UniProt:P0ACL9]]
[http://www.ncbi.nlm.nih.gov/gene?term=944827 GeneID:944827]
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Escherichia coli str. K-12 substr. MG1655
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[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
[[RegulonDB]]
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[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_414655 RefSeq:NP_414655]
RegulonDB:ECK120001076
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
[[EchoBASE]]
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[http://salilab.org/modbase/searchbyid?databaseID=P0ACL9 ModBase:P0ACL9]
EchoBASE:EB1080
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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==References==
==References==
{{BacktoTop}}
{{BacktoTop}}
 
{{RefHelp}}
<references/>
<references />
__NOTOC__
__NOTOC__
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===Categories===
===Categories===
{{BacktoTop}}
{{BacktoTop}}
[[Category:Proteins]]
[[Category:Proteins]]
[[Category:GO:0006350_!_transcription]][[Category:GO:0006096_!_glycolysis]][[Category:GO:0016564_!_transcription repressor activity]][[Category:GO:0005737_!_cytoplasm]]

Latest revision as of 20:21, 17 February 2015

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

PdhR

Synonyms

DNA-binding transcriptional dual regulator[1], B0113[2][1], YacB[2][1], GenA[2][1], PdhR[2][1] , aceC, ECK0112, genA, JW0109, yacB, b0113

Product description

PdhR transcriptional dual regulator[2][3]

Pyruvate dehydrogenase operon (pdhR-aceEF-lpd) repressor; autoregulatory; pyruvate relieves repression; monomeric[4]

EC number (for enzymes)



Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000524

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:2060763[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P10585
UniProtKB:P0A8V6
UniProtKB:P12380
UniProtKB:P22773

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:7783622[6]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:8057842[7]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:8262214[8]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000524

C

Seeded from EcoCyc (v14.0)

complete

GO:0016563

transcription activator activity

PMID:2060763[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P10585
UniProtKB:P0A8V6
UniProtKB:P12380
UniProtKB:P22773

F

Seeded from EcoCyc (v14.0)

complete

GO:0016563

transcription activator activity

PMID:7783622[6]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0016563

transcription activator activity

PMID:8057842[7]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0016563

transcription activator activity

PMID:8262214[8]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0016566

specific transcriptional repressor activity

PMID:2060763[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P10585
UniProtKB:P0A8V6
UniProtKB:P12380
UniProtKB:P22773

F

Seeded from EcoCyc (v14.0)

complete

GO:0016566

specific transcriptional repressor activity

PMID:7783622[6]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0016566

specific transcriptional repressor activity

PMID:8057842[7]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0016566

specific transcriptional repressor activity

PMID:8262214[8]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0032582

negative regulation of gene-specific transcription

PMID:2060763[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P10585
UniProtKB:P0A8V6
UniProtKB:P12380
UniProtKB:P22773

P

Seeded from EcoCyc (v14.0)

complete

GO:0032582

negative regulation of gene-specific transcription

PMID:7783622[6]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0032582

negative regulation of gene-specific transcription

PMID:8057842[7]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0032582

negative regulation of gene-specific transcription

PMID:8262214[8]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0043193

positive regulation of gene-specific transcription

PMID:2060763[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P10585
UniProtKB:P0A8V6
UniProtKB:P12380
UniProtKB:P22773

P

Seeded from EcoCyc (v14.0)

complete

GO:0043193

positive regulation of gene-specific transcription

PMID:7783622[6]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0043193

positive regulation of gene-specific transcription

PMID:8057842[7]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0043193

positive regulation of gene-specific transcription

PMID:8262214[8]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

aceF

PMID:16606699[9]

Experiment(s):EBI-1135589

Protein

tatE

PMID:16606699[9]

Experiment(s):EBI-1135589

Protein

rpmB

PMID:16606699[9]

Experiment(s):EBI-1135589

Protein

aceE

PMID:16606699[9]

Experiment(s):EBI-1135589

Protein

lpdA

PMID:16606699[9]

Experiment(s):EBI-1135589

Protein

groL

PMID:16606699[9]

Experiment(s):EBI-1135589


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes


Notes

Structure and Physical Properties

[back to top]


Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MAYSKIRQPK LSDVIEQQLE FLILEGTLRP GEKLPPEREL AKQFDVSRPS LREAIQRLEA
KGLLLRRQGG GTFVQSSLWQ SFSDPLVELL SDHPESQYDL LETRHALEGI AAYYAALRST
DEDKERIREL HHAIELAQQS GDLDAESNAV LQYQIAVTEA AHNVVLLHLL RCMEPMLAQN
VRQNFELLYS RREMLPLVSS HRTRIFEAIM AGKPEEAREA SHRHLAFIEE ILLDRSREES
RRERSLRRLE QRKN
Length

254

Mol. Wt

29.426 kDa

pI

6.4 (calculated)

Extinction coefficient

14,440 - 14,565 (calc based on 6 Y, 1 W, and 1 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

11..74

PF00392 Bacterial regulatory proteins, gntR family

PMID:19920124[10]

Domain

99..227

PF07729 FCD domain

PMID:19920124[10]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=pdhR taxon=562,83333 </beststructure>

Models

View models at:

Structure figures

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference


Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128106

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:944827

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0000394

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0ACL9

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11088

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11088

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:944827

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001076

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1080

Escherichia coli str. K-12 substr. MG1655


Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 5.4 Haydon, DJ & Guest, JR (1991) A new family of bacterial regulatory proteins. FEMS Microbiol. Lett. 63 291-5 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 Quail, MA & Guest, JR (1995) Purification, characterization and mode of action of PdhR, the transcriptional repressor of the pdhR-aceEF-lpd operon of Escherichia coli. Mol. Microbiol. 15 519-29 PubMed
  7. ↑ 7.0 7.1 7.2 7.3 7.4 Quail, MA et al. (1994) The pdhR-aceEF-lpd operon of Escherichia coli expresses the pyruvate dehydrogenase complex. Mol. Microbiol. 12 95-104 PubMed
  8. ↑ 8.0 8.1 8.2 8.3 8.4 Haydon, DJ et al. (1993) A mutation causing constitutive synthesis of the pyruvate dehydrogenase complex in Escherichia coli is located within the pdhR gene. FEBS Lett. 336 43-7 PubMed
  9. ↑ 9.0 9.1 9.2 9.3 9.4 9.5 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  10. ↑ 10.0 10.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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