ygaP:Gene Product(s): Difference between revisions

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!align=left {{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
||
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predicted inner membrane protein with hydrolase activity<ref name='LIB:Riley_2006'/>, B2668<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgaP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''predicted inner membrane protein with hydrolase activity<ref name='LIB:Riley_2006'/>, B2668<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgaP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2662, JW2643, b2668''
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!align=left {{table heading style}} |Product description
!align=left {{table heading style}} |Product description
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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GO:0016020
GO:0005886
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|
membrane
plasma membrane
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GO_REF:0000004<br />GO_REF:0000004
GOA:spkw<br />SP_KW:GO_REF:0000004
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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SP_KW:KW-0397<br />SP_KW:KW-0472
SP_KW:KW-0997
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C
C
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
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complete  
complete  
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plasma membrane
plasma membrane
|
|
GO_REF:0000004<br />GO_REF:0000004<br />GO_REF:0000023
GOA:spkw<br />SP_KW:GO_REF:0000004
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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SP_KW:KW-0997<br />SP_KW:KW-1003<br />SP_SL:SL-0037
SP_KW:KW-1003
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C
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
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complete
|-
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GO:0016020
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membrane
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GOA:spkw<br />SP_KW:GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0472
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C
|
Seeded from [[EcoCyc]] (v14.0)
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complete  
complete  
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integral to membrane
integral to membrane
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|
GO_REF:0000004
GOA:spkw<br />SP_KW:GO_REF:0000004
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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C
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
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complete  
complete  
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GO:0016021
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integral to membrane
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GO_REF:0000023
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IEA: Inferred from Electronic Annotation
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SP_SL:SL-9909
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C
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Seeded from [[EcoCyc]] (v14.0)
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complete
 
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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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Experiment(s):EBI-1143617<br />  
Experiment(s):EBI-1143617<br />  


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!|Compartment!!Description!!Evidence!!Notes
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
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Daley et al. (2005) <ref name=PMID:15919996/>
Daley et al. (2005) <ref name=PMID:15919996/>
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!align=left {{table heading style}} |Name
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IFHCQAGKRT SNNADKLAAI AAPAEIFLLE DGIDGWKKAG LPVAVNKSQP LPLMRQVQIA
IFHCQAGKRT SNNADKLAAI AAPAEIFLLE DGIDGWKKAG LPVAVNKSQP LPLMRQVQIA
AGGLILIGVV LGYTVNSGFF LLSGFVGAGL LFAGISGFCG MARLLDKMPW NQRA</pre>  
AGGLILIGVV LGYTVNSGFF LLSGFVGAGL LFAGISGFCG MARLLDKMPW NQRA</pre>  
|-
!align=left {{table heading style}} |Length
||
174
|-
|-
!align=left {{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
||
||
18.64 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
18.639 kDa
|-
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!align=left {{table heading style}} |pI
!align=left {{table heading style}} |pI
||
||
6.9 (calculated)
|-
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!align=left {{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
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13980 - 14230 (calc based on 2 Y, 2 W, and 2 C residues)  
13,980 - 14,230 (calc based on 2 Y, 2 W, and 2 C residues)


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!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References
|-  
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Domain
Domain
|
|
15 - 105
7..99
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[[interpro:IPR001763|Rhodanese]]
[http://pfam.janelia.org/family/PF00581 PF00581  Rhodanese-like domain]
|
 
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|
[http://www.uniprot.org/uniprot/P55734#section_features UniProt:P55734]
PMID:19920124
|-  
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Domain
Domain
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|
119 - 141
112..174
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Predicted membrane-spanning helix.
[http://pfam.janelia.org/family/PF11127 PF11127  Protein of unknown function (DUF2892)]
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TMD predicted by [http://www.cbs.dtu.dk/services/TMHMM TMHMM]<ref name='PMID:11152613' />
 
|-
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Domain
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146 - 165
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Predicted membrane-spanning helix.
|
|
TMD predicted by [http://www.cbs.dtu.dk/services/TMHMM TMHMM]<ref name='PMID:11152613' />
PMID:19920124


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</td>
</td>
<td>
<td>
<!-- motifs column 2-->
<motif_map/>
{{TMHMM Picture|ygaP}}
{{TMHMM Picture|ygaP}}
</td>
</td>
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</table>


<span id="Structure"></span><big>'''Structure'''</big>
<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
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!align=left {{table heading style}} |Structures
!align=left {{table heading style}} |Structures
||
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<beststructure>ygaP
<beststructure>
562</beststructure>
gene=ygaP
 
taxon=562,83333
</beststructure>
|-
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!align=left {{table heading style}} |Models
!align=left {{table heading style}} |Models
||
||
View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=ygaP&sub=keywordSearc EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/P55734 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=ygaP&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P55734 PSI-PRED (P55734)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P55734 Genomes TO Protein (P55734)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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<!--Structure_notes--></protect>
</td><td></protect>
==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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===Notes===
===Notes===


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!|Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference


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!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-  
|-  
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[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=G7398-MONOMER EcoCyc:G7398-MONOMER]
[http://www.ncbi.nlm.nih.gov/protein/16130582 GI:16130582]
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Escherichia coli str. K-12 substr. MG1655
|-
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[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_417154.1 GeneID:947135]
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Escherichia coli str. K-12 substr. MG1655
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[[ASAP]]
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ASAP:ABE-0008786
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
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[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P55734 UniProtKB/Swiss-Prot:P55734]
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Escherichia coli str. K-12 substr. MG1655
|-
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[[EcoCyc]]
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EcoCyc:G7398
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
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[[EcoGene]]
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EcoGene:EG13288
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
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|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
|
[[uniprot:P55734|UniProt:P55734]]
[http://www.ncbi.nlm.nih.gov/gene?term=947135 GeneID:947135]
|
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Escherichia coli str. K-12 substr. MG1655
|-  
|-  
|
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
[[RegulonDB]]
|
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_417154 RefSeq:NP_417154]
RegulonDB:ECK120003965
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
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[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
[[EchoBASE]]
|
|
[http://salilab.org/modbase/searchbyid?databaseID=P55734 ModBase:P55734]
EchoBASE:EB3073
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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==References==
==References==
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===Categories===
===Categories===
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[[Category:Proteins]]
[[Category:Proteins]]
[[Category:Pfam:PF00581_!_Rhodanese-like domain]]
[[Category:Pfam:PF11127_!_Protein of unknown function (DUF2892)]]

Latest revision as of 20:54, 17 February 2015

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YgaP

Synonyms

predicted inner membrane protein with hydrolase activity[1], B2668[2][1], YgaP[2][1] , ECK2662, JW2643, b2668

Product description

predicted inner membrane protein with hydrolase activity[2][3]

Function unknown, rhodanese activity in vitro; tributyltin-inducible via YgaU[4]

EC number (for enzymes)



Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rpsI

PMID:16606699[5]

Experiment(s):EBI-1143617

Protein

groL

PMID:16606699[5]

Experiment(s):EBI-1143617

Protein

yaaI

PMID:16606699[5]

Experiment(s):EBI-1143617

Protein

rplB

PMID:16606699[5]

Experiment(s):EBI-1143617


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 2 predicted transmembrane domains

Daley et al. (2005) [6]



Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MALTTISPHD AQELIARGAK LIDIRDADEY LREHIPEADL APLSVLEQSG LPAKLRHEQI
IFHCQAGKRT SNNADKLAAI AAPAEIFLLE DGIDGWKKAG LPVAVNKSQP LPLMRQVQIA
AGGLILIGVV LGYTVNSGFF LLSGFVGAGL LFAGISGFCG MARLLDKMPW NQRA
Length

174

Mol. Wt

18.639 kDa

pI

6.9 (calculated)

Extinction coefficient

13,980 - 14,230 (calc based on 2 Y, 2 W, and 2 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

7..99

PF00581 Rhodanese-like domain

PMID:19920124[7]

Domain

112..174

PF11127 Protein of unknown function (DUF2892)

PMID:19920124[7]

<motif_map/>

tmhmm.php?gene=ygaP&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=ygaP taxon=562,83333 </beststructure>

Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference


Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130582

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947135

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0008786

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P55734

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7398

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13288

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947135

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003965

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3073

Escherichia coli str. K-12 substr. MG1655


Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  7. ↑ 7.0 7.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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